B4380
溴乙烷
≥97% purity, powder
别名:
单溴代二苯甲烷
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关于此项目
经验公式（希尔记法）:
C10H11BrN2O2
化学文摘社编号:
分子量:
271.11
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Beilstein/REAXYS Number:
4430959
产品名称
溴乙烷, ≥97% (HPLC)
InChI
1S/C10H11BrN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3
SMILES string
CC1=C(C)C(=O)N2N1C(CBr)=C(C)C2=O
InChI key
AHEWZZJEDQVLOP-UHFFFAOYSA-N
assay
≥97% (HPLC)
form
powder
color
yellow
mp
161 °C
solubility
acetonitrile: 20 mg/mL
ε (extinction coefficient)
4.6-5.1 at 396-398 nm in H2O
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
Quality Level
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Application
溴代双满用于高效液相色谱法硫醇测定,适于荧光测定2，3-二巯基丙烷-1-磺酸和其他二硫醇。溴代双满已用作研究牛心线粒体寡霉素敏感性 ATP 酶的荧光标记。
此物质可用于体内和体外游离硫化氢的定量测定。它已用于标记含有硫醇基的蛋白质。
此物质可用于体内和体外游离硫化氢的定量测定。它已用于标记含有硫醇基的蛋白质。
Biochem/physiol Actions
溶液形式的溴代双满可与小分子硫醇基（如 GSH）和反应性蛋白硫醇基（如血红蛋白）反应。溴代双满与硫醇的反应为二级pH依赖性反应，且在与硫醇盐反应后，可活化水溶性荧光产物以便检测。
General description
溴代双满又称单溴联苯胺。它还是一种已知的硫醇探针，是一种在光解反应后活化的荧光试剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
N S Kosower et al.
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The bimane fluorescent labels, monobromobimane, dibromobimane, and monobromotrimethylammoniobimane, are derivatives of syn-9,10-dioxabimane:1,5-diazabicyclo[3.3.0]octa-3,6-diene-2,8-dione. They efficiently label hemoglobin (reactive thiol groups), membrane proteins, and glutathione of normal human red cells under physiological conditions. Monobromobimane and dibromobimane are effective on intact cells while
Differing effects of mechanical dough development and sheeting development methods on aggregated glutenin proteins.
Sutton KH, et al.
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Edward A Wintner et al.
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Hydrogen sulphide (H(2)S) is a labile, endogenous metabolite of cysteine, with multiple biological roles. The development of sulphide-based therapies for human diseases will benefit from a reliable method of quantifying H(2)S in blood and tissues. Concentrations of reactive sulphide in
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Bromobimane probes for thiols.
E M Kosower et al.
Methods in enzymology, 251, 133-148 (1995-01-01)
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