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质量水平
方案
≥98% (HPLC and TLC)
表单
powder
mp
280 °C
溶解性
H2O: 10 mg/mL
water and ethanol: 10 mg/mL
phosphate buffer: precipitates
适用性
passes application test for fluorescence
应用
diagnostic assay manufacturing
hematology
histology
储存温度
−20°C
SMILES字符串
Cl[H].Cl[H].Cl[H].[H]O[H].CN1CCN(CC1)c2ccc3NC(=NCc3c2)c4ccc5NC(=NCc5c4)c6ccc(O)cc6
InChI
1S/C27H28N6O.3ClH.H2O/c1-32-10-12-33(13-11-32)22-5-9-25-21(15-22)17-29-27(31-25)19-4-8-24-20(14-19)16-28-26(30-24)18-2-6-23(34)7-3-18;;;;/h2-9,14-15,34H,10-13,16-17H2,1H3,(H,28,30)(H,29,31);3*1H;1H2
InChI key
OWRSPPSBNWJJAR-UHFFFAOYSA-N
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应用
bisBenzimide H 33258可用于DNA、染色体和细胞核的染色。 bisBenzimide H 33258可用于荧光显微术或流式细胞术。
最大激发波长= 346nm
最大发射波长= 460nm
最大激发波长= 346nm
最大发射波长= 460nm
bisBenzimide H 33258已用于细胞中的核染色。
生化/生理作用
bisBenzimide H 33258是一种有效的选择性Bcl-XL抑制剂。 bisBenzimide H 33258是一种膜可渗透的荧光DNA染色剂，具有低细胞毒性，可嵌入DNA的A-T区域。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Florian Ehrlich et al.
Scientific reports, 9(1), 10924-10924 (2019-07-31)
Keratins are the main cytoskeletal proteins of epithelial cells and changes in the expression of keratins have contributed to the evolutionary adaptation of epithelia to different environments. Keratin K24 was proposed to be a differentiation marker of epidermal keratinocytes but
Cell alignment induced by anisotropic electrospun fibrous scaffolds alone has limited effect on cardiomyocyte maturation.
Han J, et al.
Stem Cell Research, 16, 740-750 (2016)
Zev A Binder et al.
Cancer cell, 34(1), 163-177 (2018-07-11)
We explored the clinical and pathological impact of epidermal growth factor receptor (EGFR) extracellular domain missense mutations. Retrospective assessment of 260 de novo glioblastoma patients revealed a significant reduction in overall survival of patients having tumors with EGFR mutations at
Susanna Fiorelli et al.
Cells, 8(4) (2019-04-19)
Reactive oxygen species (ROS) induce nuclear factor erythroid 2-related factor 2 (Nrf2) activation as an adaptive defense mechanism, determining the synthesis of antioxidant molecules, including heme-oxygenase-1 (HO-1). HO-1 protects cells against oxidative injury, degrading free heme and inhibiting ROS production.
Spontaneous and continuous cyclooxygenase-2-dependent prostaglandin E2 production by stromal cells in the murine small intestine lamina propria: directing the tone of the intestinal immune response.
Newberry RD, et al.
Journal of Immunology, 166, 4465-4472 (2001)
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