推荐产品
等级
analytical standard
质量水平
药品控制
USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
格式
neat
储存温度
−20°C
SMILES字符串
OC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1OC(=O)c3ccccc3)N2
InChI
1S/C15H17NO4/c17-14(18)13-11-7-6-10(16-11)8-12(13)20-15(19)9-4-2-1-3-5-9/h1-5,10-13,16H,6-8H2,(H,17,18)/t10-,11+,12-,13+/m0/s1
InChI key
CMYJDRSCSOXYHG-QNWHQSFQSA-N
一般描述
Benzoylnorecgonine is a major urinary metabolite of cocaine, which can be determined by a variety of analytical techniques and is often used in toxicology screening to confirm cocaine abuse.
应用
Benzoylnorecgonine may be used as an analytical reference standard for the quantification of the analyte in cocaine based products using high-performance liquid chromatography.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Skin Sens. 1
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
监管及禁止进口产品
Feiyu Yang et al.
Journal of separation science, 40(21), 4234-4245 (2017-08-27)
An easy-to-handle magnetic dispersive solid-phase extraction procedure was developed for preconcentration and extraction of cocaine and cocaine metabolites in human urine. Divinyl benzene and vinyl pyrrolidone functionalized silanized Fe
R J Konkol et al.
Journal of child neurology, 9(3), 242-248 (1994-07-01)
Recent reports indicate that cocaine metabolites have biologic activity and could be toxic. To explore this possibility, two studies were initiated. The first study aimed to define the distribution of cocaine species by quantifying levels of cocaine and its metabolites
C E Lau et al.
Journal of chromatography, 532(1), 95-103 (1990-10-26)
A single, isocratic high-performance liquid chromatographic method is described for the determination of cocaine and three of its metabolites along with caffeine in serum microsamples (50 microliters). The small sample size permits the tracking of pharmacokinetic data over time in
R A Dean et al.
Toxicology and applied pharmacology, 117(1), 1-8 (1992-11-01)
The coabuse of cocaine and ethanol occurs with high frequency and increases the risk of cocaine-related morbidity and mortality. The mechanisms mediating the toxic interactions of cocaine and ethanol are not clearly defined. This study examined the effects of acute
J A Sandberg et al.
The Journal of pharmacology and experimental therapeutics, 258(2), 477-482 (1991-08-01)
The pharmacokinetics of cocaine (COC) were studied during late gestation in guinea pigs. Clearance (Cl) was not dose-dependent and the average +/- S.D. was 59 +/- 16 ml/min/kg over the i.v. dose range of 2 to 12 mg/kg. Volume of
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