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Merck
CN

B1385

布托沙明 盐酸盐

analytical standard, for drug analysis, mixture of diastereomers

别名:

α-(1-[t-丁基氨基]乙基)-2,5-二甲氧基苯甲醇

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关于此项目

经验公式(希尔记法):
C15H25NO3 · HCl
化学文摘社编号:
分子量:
303.82
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
227-169-5
MDL number:
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InChI key

URPAECSKKQLCII-UHFFFAOYSA-N

InChI

1S/C15H25NO3.ClH/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6;/h7-10,14,16-17H,1-6H3;1H

SMILES string

Cl.COc1ccc(OC)c(c1)C(O)C(C)NC(C)(C)C

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

General description

盐酸布他沙明是一种β-肾上腺素受体拮抗剂,具有β2-选择性。

Application

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

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Claudio Molinari et al.
Endocrinology, 148(8), 4080-4090 (2007-04-28)
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Nozomu Abe et al.
BioMed research international, 2020, 3214186-3214186 (2020-05-29)
Adrenaline quickly inhibits the release of histamine from mast cells. Besides β2-adrenergic receptors, several in vitro studies also indicate the involvement of α-adrenergic receptors in the process of exocytosis. Since exocytosis in mast cells can be detected electrophysiologically by the
Jiayin Lu et al.
International journal of molecular sciences, 22(3) (2021-02-06)
Restraint stress causes various maternal diseases during pregnancy. β2-Adrenergic receptor (β2-AR) and Forkhead transcription factor class O 1 (FOXO1) are critical factors not only in stress, but also in reproduction. However, the role of FOXO1 in restraint stress, causing changes
Nan Yang et al.
Respiratory research, 22(1), 65-65 (2021-02-25)
Airway inflammation is a key feature of chronic obstructive pulmonary disease (COPD) and inhaled corticosteroids (ICS) remain the main treatment for airway inflammation. Studies have noted the increased efficacy of ICS and long-acting beta 2 agonist (LABA) combination therapy in
Concise Dictionary of Pharmacological Agents: Properties and Synonyms null

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