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等级
analytical standard
质量水平
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
SMILES字符串
CCCCOc1ccc(CC(=O)NO)cc1
InChI
1S/C12H17NO3/c1-2-3-8-16-11-6-4-10(5-7-11)9-12(14)13-15/h4-7,15H,2-3,8-9H2,1H3,(H,13,14)
InChI key
MXJWRABVEGLYDG-UHFFFAOYSA-N
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一般描述
Bufexamac is a drug with antipyretic, analgesic and anti-inflammatory properties.
应用
Bufexamac may be used as a reference standard in the determination of bufexamac in pharmaceutical formulations using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
推荐产品
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Contact sensitivity to bufexamac.
Lachapelle JM.
Contact Dermatitis, 1(4), 261-261 (1975)
EMA revokes marketing authorization for bufexamac.
Wolfgang Uter et al.
Contact dermatitis, 64(4), 235-236 (2011-03-12)
P H Marttinen et al.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 53(6), 311-318 (2006-08-12)
The objective here was to evaluate the acute effects of induced arthritis on synovial fluid (SF) levels of matrix metalloproteinases (MMP) -2, -8 and -9 in horses. To evaluate MMP-2 and -9 activities and the effect of non-steroidal anti-inflammatory drug
Allergic contact dermatitis with spreading over extensive regions due to topical use of 5% bufexamac ointment.
Junko Arikawa et al.
The Journal of dermatology, 31(2), 136-138 (2004-05-27)
Yoshiki Seto et al.
Journal of pharmaceutical and biomedical analysis, 55(3), 591-596 (2011-03-25)
The present study aimed to modulate the photoreactivity of bufexamac, with a focus on photostability and phototoxicity, by forming an inclusion complex with sulfobutylether-β-cyclodextrin (SBECD). The photobiochemical properties of bufexamac were evaluated by reactive oxygen species (ROS) assay and using
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