产品名称
苯佐卡因, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3
SMILES string
CCOC(=O)c1ccc(N)cc1
InChI key
BLFLLBZGZJTVJG-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
benzocaine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
Benzocaine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
233.6 °F
flash_point_c
112 °C
Methemoglobinemia: a complication after fiberoptic orotracheal intubation with benzocaine spray. A case report.
F D Ellis et al.
The Journal of bone and joint surgery. American volume, 77(6), 937-939 (1995-06-01)
H A Cooper
Southern medical journal, 90(9), 946-948 (1997-09-26)
Acute methemoglobinemia is a medical emergency that can rapidly become fatal. A substantial number of drugs, including topical preparations, can precipitate this condition. I report a rare example of severe, acute methemoglobinemia caused by oropharyngeal anesthesia with topical benzocaine spray
L A Linares et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 18(3), 267-269 (1990-07-01)
Methemoglobinemia is a condition in which more than 2% of the hemoglobin of the blood has been oxidized to the ferric form, a molecule which is incapable of binding oxygen or carbon dioxide. Clinically, the patient appears lethargic, cyanotic, and
Stephan Warnke et al.
Journal of the American Chemical Society, 137(12), 4236-4242 (2015-03-12)
The immediate environment of a molecule can have a profound influence on its properties. Benzocaine, the ethyl ester of para-aminobenzoic acid that finds an application as a local anesthetic, is found to adopt in its protonated form at least two
L F Rodriguez et al.
The Annals of pharmacotherapy, 28(5), 643-649 (1994-05-01)
To report a case of benzocaine-induced inethemoglobinemia and present a review of the related literature. An 83-year-old man received benzocaine topical anesthesia 600 mg prior to intubation for resection of a thyroid adenoma. The patient became severely cyanotic after induction
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