所有图片(1)
别名:
3,6-双（二甲氨基）吖啶 盐酸盐
经验公式（希尔记法）:
C17H19N3 · HCl
CAS号:
分子量:
301.81
Beilstein:
3575587
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
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质量水平
检测方案
>95.0% (HPLC)
形式
solution
浓度
10 mg/mL in H2O
颜色
orange to red
εmax
47-54 at 486-492 nm in water
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
Cl[H].CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C
InChI
1S/C17H19N3.ClH/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14;/h5-11H,1-4H3;1H
InChI key
VSTHNGLPHBTRMB-UHFFFAOYSA-N
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应用
吖啶橙盐酸盐溶液已用于研究自噬性细胞死亡。也用于染色体的染色。
生化/生理作用
吖啶橙 (Acridine Orange) 是一种异染性染料，可以染色 DNA、RNA 和酸性糖胺聚糖。低浓度时嵌入 DNA 并沉淀 RNA。然而，在高浓度时，它使 RNA 和 DNA 变性并沉淀。吖啶橙也用于分析自噬。以 pH 依赖性方式进入酸性细胞器。在中性 pH 条件下，吖啶橙发出绿色荧光，在酸性条件下，吖啶橙在酸性细胞器中聚集，发出鲜红色荧光。
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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