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安全信息

A7284

Sigma-Aldrich

白蛋白 溶液 来源于牛血清

30%±2% in 0.85% sodium chloride, aseptically filled

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别名:
BSA溶液
CAS号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.25

生物来源

bovine

质量水平

无菌性

aseptically filled

检测方案

28-32% protein basis (biuret)

形式

solution

纯化方式

heat shock fractionation

包含

0.1% sodium azide as preservative

不包含

stabilizer

来源

USA origin

浓度

28-32% protein (biuret)
30%±2% in 0.85% sodium chloride

技术

ELISA: suitable

UniProt登记号

储存温度

2-8°C

基因信息

bovine ... ALB(280717)

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一般描述

牛血清白蛋白 (BSA) 在17个半胱氨酸残基交联的单链中结合。它包含三个同源、结构不同的结构域和两个亚结构域。这种球状、α-螺旋、非糖基化蛋白质在肝脏中生成。

应用

牛血清白蛋白溶液已用于:
  • 研究血浆蛋白对硫酸化糖胺聚糖 (sGAGs) 的影响
  • 组织学评估植入的同种异体间充质干细胞 (MSCs) 藻酸盐构建体
  • 用作磷酸盐缓冲盐水 (PBS) 成分,处理红细胞 (RBC) 以便样品制备

生化/生理作用

牛血清白蛋白 (BSA) 是酶联免疫吸附测定 (ELISA) 使用最广泛的封闭剂。它还是细胞培养基的主要成分。BSA可促进人胚胎干细胞(hESC)分化,协助药物、激素和脂肪酸循环。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

含少量动物源组分生物产品

分析证书(COA)

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Sohrab Khatab et al.
Cell biology and toxicology, 36(6), 553-570 (2020-06-01)
Mesenchymal stem cells (MSC) are promising candidates for use as a biological therapeutic. Since locally injected MSC disappear within a few weeks, we hypothesize that efficacy of MSC can be enhanced by prolonging their presence. Previously, encapsulation in alginate was
Emily M Thrash et al.
STAR protocols, 1(2), 100055-100055 (2020-10-29)
As mass cytometry (MC) is implemented in clinical settings, the need for robust, validated protocols that reduce batch effects between samples becomes increasingly important. Here, we present a streamlined MC workflow for high-throughput staining that generates reproducible data for up
M J Leijs et al.
European cells & materials, 33, 43-58 (2017-02-01)
Bone marrow derived mesenchymal stem cells (MSCs) have immunomodulatory and trophic capacities. For therapeutic application in local chronic inflammatory diseases, MSCs, preferably of allogeneic origin, have to retain immunomodulatory properties. This might be achieved by encapsulation of MSCs in a
R Zhao et al.
Biorheology, 47(3-4), 193-203 (2010-11-19)
The accumulation of platelets near the blood vessel wall or artificial surface is an important factor in the cascade of events responsible for coagulation and/or thrombosis. In small blood vessels and flow channels this phenomenon has been attributed to the
Brent L Wood
Current protocols in cytometry, 93(1), e73-e73 (2020-04-21)
The identification of residual leukemia following therapy, termed minimal or measurable residual disease (MRD), has emerged as one of the most important prognostic factors for patients with acute leukemia, including acute myeloid leukemia (AML). Flow cytometry is a preferred method

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