所有图片(1)
About This Item
经验公式（希尔记法）:
C12H15N3O2S
CAS号:
分子量:
265.33
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
检测方案
≥98%
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
SMILES字符串
CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1
InChI
1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
InChI key
HXHWSAZORRCQMX-UHFFFAOYSA-N
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一般描述
化学结构：苯并咪唑
阿苯达唑是可用于治疗人胃肠道蠕虫病的苯并咪唑衍生物。它抑制微管，并阻断葡萄糖摄取，导致糖原储备的耗尽，并降低易感寄生虫幼虫和成虫阶段的三磷酸腺苷（ATP）的形成。
应用
有关合适的仪器技术的更多信息，请参阅产品的分析证书。如需进一步支持，请联系技术服务。
阿苯达唑可用作小鼠血浆中高效液相色谱法（HPLC）测定阿苯达唑及其主要代谢物（阿苯达唑亚砜和阿苯达唑砜）的参考标准。
生化/生理作用
结合微管蛋白并抑制微管的聚合。
警示用语：
Warning
危险声明
危险分类
Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral
靶器官
Adrenal gland,Blood,male reproductive organs,spleen
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
农药列管产品
H D Solana et al.
Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y [de] la Asociacion Latinoamericana de Farmacologia, 48(4), 199-205 (1999-01-23)
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Quantitative determination of albendazole and its main metabolites in plasma.
Garcia J J, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 723(1-2), 265-271 (1999)
Martin Spicher et al.
Antimicrobial agents and chemotherapy, 52(9), 3447-3450 (2008-07-16)
In vitro treatment of Echinococcus multilocularis and Echinococcus granulosus larval stages with the antimalarials dihydroartemisinin and artesunate (10 to 40 microM) exhibited promising results, while 6 weeks of in vivo treatment of mice infected with E. multilocularis metacestodes (200 mg/kg
Role of excipients in the crystallization of Albendazole.
Raval M K, et al.
Advanced Powder Technology, 26(4), 1102-1115 (2015)
Albendazole as a promising molecule for tumor control.
Castro L S E P W, et al.
Redox Biology, 10, 90-99 (2016)
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