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Merck
CN

A42409

Sigma-Aldrich

2-氨基联苯

≥96.5% purity, powder or crystals

别名:

2-联苯胺, 邻苯基苯胺

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About This Item

线性分子式:
C6H5C6H4NH2
CAS号:
分子量:
169.22
Beilstein:
471874
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

产品名称

2-氨基联苯, ≥96.5% (GC)

蒸汽密度

5.8 (vs air)

质量水平

方案

≥96.5% (GC)

表单

powder or crystals

自燃温度

842 °F

技术

titration: suitable

杂质

<0.1% 4-aminobiphenyl

颜色

brown
off-white to yellow

沸点

299 °C (lit.)

mp

47-50 °C (lit.)

溶解性

water: insoluble

密度

1.16 g/cm3 at 21 °C

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

Nc1ccccc1-c2ccccc2

InChI

1S/C12H11N/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H,13H2

InChI key

TWBPWBPGNQWFSJ-UHFFFAOYSA-N

基因信息

human ... UGT1A4(54657)

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一般描述

2-氨基联苯是UGT(UDP-葡糖醛酸转移酶)的底物,包括UGT1A4、UGT2B13和UGT2B16。

象形图

Health hazardExclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

307.4 °F - closed cup

闪点(°C)

153 °C - closed cup

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Identification of the rabbit liver UDP-glucuronosyltransferase catalyzing the glucuronidation of 4-ethoxyphenylurea (dulcin).
Uesawa Y, et al.
Drug Metabolism and Disposition, 32, 1476-1481 (2004)
S Kimura et al.
Carcinogenesis, 20(9), 1825-1830 (1999-09-02)
4-Aminobiphenyl (4-ABP), a potent carcinogen in rodents (liver cancer) and human (bladder cancer), is found as an environmental contaminant and in tobacco smoke. Hemoglobin adducts and lung DNA adducts of 4-ABP are found in tobacco smokers. In vitro metabolism studies
Y Yamazoe et al.
Xenobiotica; the fate of foreign compounds in biological systems, 14(7), 549-552 (1984-07-01)
The involvement of four forms of cytochrome P-450 in the activation of the promutagens, 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), 2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-aminofluorene and 4-aminobiphenyl has been investigated using a Salmonella test system. A high-spin form, P-448 II-a, catalysed the activation of
R Harzmann et al.
Urologia internationalis, 35(5), 340-350 (1980-01-01)
It takes 24 months to induce preinvasive carcinomas in the urinary bladder of dogs as reported in the literature. The transplantation of chemically induced carcinomas has never been successful. Therefore, it was looked for methods which enable a shortening of
High-performance liquid chromatography with on-line radioactivity monitoring for metabolic studies of 2- and 4-[14C]aminobiphenyls.
S D Jatoe et al.
Journal of chromatography, 442, 394-400 (1988-06-17)

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