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产品名称
2-氨基联苯, ≥96.5% (GC)
蒸汽密度
5.8 (vs air)
质量水平
方案
≥96.5% (GC)
表单
powder or crystals
自燃温度
842 °F
技术
titration: suitable
杂质
<0.1% 4-aminobiphenyl
颜色
brown
off-white to yellow
沸点
299 °C (lit.)
mp
47-50 °C (lit.)
溶解性
water: insoluble
密度
1.16 g/cm3 at 21 °C
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
Nc1ccccc1-c2ccccc2
InChI
1S/C12H11N/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H,13H2
InChI key
TWBPWBPGNQWFSJ-UHFFFAOYSA-N
基因信息
human ... UGT1A4(54657)
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一般描述
2-氨基联苯是UGT(UDP-葡糖醛酸转移酶)的底物,包括UGT1A4、UGT2B13和UGT2B16。
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
307.4 °F - closed cup
闪点(°C)
153 °C - closed cup
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
Identification of the rabbit liver UDP-glucuronosyltransferase catalyzing the glucuronidation of 4-ethoxyphenylurea (dulcin).
Uesawa Y, et al.
Drug Metabolism and Disposition, 32, 1476-1481 (2004)
S Kimura et al.
Carcinogenesis, 20(9), 1825-1830 (1999-09-02)
4-Aminobiphenyl (4-ABP), a potent carcinogen in rodents (liver cancer) and human (bladder cancer), is found as an environmental contaminant and in tobacco smoke. Hemoglobin adducts and lung DNA adducts of 4-ABP are found in tobacco smokers. In vitro metabolism studies
Y Yamazoe et al.
Xenobiotica; the fate of foreign compounds in biological systems, 14(7), 549-552 (1984-07-01)
The involvement of four forms of cytochrome P-450 in the activation of the promutagens, 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), 2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-aminofluorene and 4-aminobiphenyl has been investigated using a Salmonella test system. A high-spin form, P-448 II-a, catalysed the activation of
R Harzmann et al.
Urologia internationalis, 35(5), 340-350 (1980-01-01)
It takes 24 months to induce preinvasive carcinomas in the urinary bladder of dogs as reported in the literature. The transplantation of chemically induced carcinomas has never been successful. Therefore, it was looked for methods which enable a shortening of
High-performance liquid chromatography with on-line radioactivity monitoring for metabolic studies of 2- and 4-[14C]aminobiphenyls.
S D Jatoe et al.
Journal of chromatography, 442, 394-400 (1988-06-17)
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