product name
2-氨基联苯, ≥96.5% (GC)
蒸汽密度
5.8 (vs air)
质量水平
检测方案
≥96.5% (GC)
形式
powder or crystals
自燃温度
842 °F
杂质
<0.1% 4-aminobiphenyl
颜色
brown
off-white to yellow
bp
299 °C (lit.)
mp
47-50 °C (lit.)
溶解性
water: insoluble
密度
1.16 g/cm3 at 21 °C
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
Nc1ccccc1-c2ccccc2
InChI
1S/C12H11N/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H,13H2
InChI key
TWBPWBPGNQWFSJ-UHFFFAOYSA-N
基因信息
human ... UGT1A4(54657)
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一般描述
2-氨基联苯是UGT（UDP-葡糖醛酸转移酶）的底物，包括UGT1A4、UGT2B13和UGT2B16。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2
WGK
WGK 2
闪点(°F)
307.4 °F
闪点(°C)
153 °C
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
M M Marques et al.
Chemical research in toxicology, 3(6), 559-565 (1990-11-01)
The complementary pentadecamers d(5'-TACTCTTCTTGACCT) (strand A) and d(5'-AGGTCAAGAAGAGTA) (strand B), which span a portion of the mouse c-Ha-ras protooncogene centered around codon 61, were synthesized by using standard beta-cyanoethyl phosphoramidite chemistry and characterized by sequence analysis. Strand A, containing a
Thin layer chromatographic separation and fluorometric determination of 4-aminobiphenyl in 2-aminobiphenyl.
J Zynger et al.
IARC scientific publications, (40)(40), 229-233 (1981-01-01)
Gerald Pratsch et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(37), 11555-11559 (2012-08-14)
Simply aqueous sodium hydroxide is sufficient to exclude ionic side reactions and to prepare 2-aminobiphenyls from aryl diazotates and anilines through a new variant of the Gomberg-Bachmann reaction (see scheme). The metal-free reaction under basic conditions allows to exploit the
Y Yamazoe et al.
Xenobiotica; the fate of foreign compounds in biological systems, 14(7), 549-552 (1984-07-01)
The involvement of four forms of cytochrome P-450 in the activation of the promutagens, 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), 2-amino-6-methyl-dipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-aminofluorene and 4-aminobiphenyl has been investigated using a Salmonella test system. A high-spin form, P-448 II-a, catalysed the activation of
S Kimura et al.
Carcinogenesis, 20(9), 1825-1830 (1999-09-02)
4-Aminobiphenyl (4-ABP), a potent carcinogen in rodents (liver cancer) and human (bladder cancer), is found as an environmental contaminant and in tobacco smoke. Hemoglobin adducts and lung DNA adducts of 4-ABP are found in tobacco smokers. In vitro metabolism studies
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