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O0200000

乌本苷

European Pharmacopoeia (EP) Reference Standard

别名:

乌本苷 八水合物, 1β,3β,5β,11α,14,19-Hexahydroxycard-20（22）-烯醇内酯-3-（6-脱氧-α-L-甘露糖苷）, G-毒毛花苷, 乌本苷

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关于此项目

经验公式（希尔记法）:
C29H44O12 · 8H2O
化学文摘社编号:
11018-89-6
分子量:
728.77
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329818827
MDL number:
MFCD00149240
Beilstein/REAXYS Number:
101712
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grade

pharmaceutical primary standard

API family

ouabain

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O.O.O.O.O.O.O.O.C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H44O12.8H2O/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31;;;;;;;;/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3;8*1H2/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-;;;;;;;;/m0......../s1

InChI key

TYBARJRCFHUHSN-DMJRSANLSA-N

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持，请访问现行药典网站。

Application

哇巴因EP参考标准品的预期用途是欧洲药典规定的实验室测试。

Packaging

本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。

Other Notes

可能适用相应的销售限制。

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 3 Inhalation - STOT RE 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

法规信息

危险化学品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Meneka Kanagaratnam et al.
The Journal of physiology, 595(11), 3471-3482 (2017-02-19)
Optic nerve axons get less excitable with warming. F-fibre latency does not shorten at temperatures above 30°C. Action potential amplitude falls when the Na Raising the temperature of optic nerve from room temperature to near physiological has effects on the
Li Meng et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 1841-1848 (2016-11-30)
The steroid Na+/K+-ATPase blocker ouabain has been shown to exhibit cytotoxic effects in various tumor cell systems. This study aimed to determine the effects of ouabain on Burkitt's lymphoma Raji cells. Ouabain treatment of Raji cells significantly inhibited cell proliferation
V Hreniukh et al.
Cell biochemistry and function, 34(8), 579-587 (2016-11-20)
The goal of the study was to estimate the effect of a selective V-type H+ -ATPase inhibitor bafilomycin A1 and nicotinic acid adenine dinucleotide phosphate (NAADP) on energetic processes in NK/Ly cell by directly measuring the respiration of isolated mitochondria
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货号GTIN
O020000004061833813461