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Merck
CN

96045

Supelco

2-(Hydroxymethyl)butyric acid sodium salt

analytical standard

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别名:
2-Ethyl-3-hydroxypropionic acid, 2-Ethylhydracrylic acid sodium salt, Sodium 2-(hydroxymethyl)butyrate
经验公式(希尔记法):
C5H9NaO3
分子量:
140.11
UNSPSC代码:
41116107

等级

analytical standard

检测方案

≥95.0% (GC)

保质期

limited shelf life, expiry date on the label

应用

clinical testing

格式

neat

储存温度

2-8°C

SMILES字符串

O=C(O[Na])C(CO)CC

一般描述

2-(Hydroxymethyl)butyric acid sodium salt is a urine organic acid, reportedly found in increased concentrations in primary hyperoxaluria type 2 patients.

应用

2-(Hydroxymethyl)butyric acid sodium salt may be used as an analytical standard for the determination of the analyte in the following:
  • Cerebrospinal fluid using two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC × GC–TOFMS).
  • Body fluids using gas chromatography-mass spectrometry (GC-MS).

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WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Use of a thick-film capillary column for the analysis of organic acids in body fluids
Meier-Augenstein W, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 615(1), 127-135 (1993)
Characterization of cerebrospinal fluid by comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry
Hartonen M, et al.
Journal of Chromatography A, 1293(2), 142-149 (2013)
Malonic aciduria in Maltese dogs: normal methylmalonic acid concentrations and malonyl?CoA decarboxylase activity in fibroblasts
O?Brien PD, et al.
Journal of inherited metabolic disease, 22(8), 883-890 (1999)
Severe child form of primary hyperoxaluria type 2-a case report revealing consequence of GRHPR deficiency on metabolism
Konkolova J, et al.
BMC Medical Genetics, 18(1), 59-59 (2017)

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