所有图片(1)
别名:
(2R,3R)-3,5,7-Trihydroxy-2-[(2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydrobenzo[1,4]dioxin-6-yl]-4-chromanone
经验公式（希尔记法）:
C25H22O10
推荐产品
等级
analytical standard
质量水平
检测方案
≥80.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
food and beverages
格式
neat
SMILES字符串
COc1cc(ccc1O)[C@@H]2Oc3ccc(cc3O[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O
InChI
1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-18-7-12(3-5-16(18)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23-,24-,25+/m0/s1
InChI key
FDQAOULAVFHKBX-WAABAYLZSA-N
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一般描述
Isosilybin B is a flavonolignan and a bioactive component present in silymarin, isolated from Silybum marianum. It is commonly used in the treatment of cirrhosis, hepatitis and prevents the liver from being exposed to toxic substances.
应用
Isosilybin B may be used as an analytical reference standard for the quantification of the analyte in compound preparations of Silybum marianum and Silybum.miltiorrhiza using high-performance liquid chromatography with photo diode array detection and electrospray ionization-mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Simultaneous determination of abietane-type diterpenes, flavonolignans and phenolic compounds in compound preparations of Silybum marianum and Salvia miltiorrhiza by HPLC-DAD-ESI MS
Zhao Y, et al.
Journal of Pharmaceutical and Biomedical Analysis, 38(3), 564-570 (2005)
Separation and characterization of silybin, isosilybin, silydianin and silychristin in milk thistle extract by liquid chromatography?electrospray tandem mass spectrometry
Lee.IJ, et al.
Journal of Chromatography A, 1116(1-2), 147-152 (2006)
Jiazeng Yang et al.
Metabolic engineering, 59, 44-52 (2020-02-01)
Silymarin extracted from milk thistle seeds, is used for treating hepatic diseases. Silybin and isosilybin are its main components, and synthesized from coupling of taxifolin and coniferyl alcohol. Here, the biosynthetic pathways of taxifolin and coniferyl alcohol were reconstructed in
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