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等级
analytical standard
质量水平
方案
≥99.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
152-155 °C (lit.)
应用
cleaning products
cosmetics
food and beverages
personal care
包装形式
neat
SMILES字符串
OCC1=CC(=O)C(O)=CO1
InChI
1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
InChI key
BEJNERDRQOWKJM-UHFFFAOYSA-N
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一般描述
曲酸是一种酪氨酸酶抑制剂,由多种真菌(包括米曲霉)产生。由于它能够与黑色素形成过程中的含铜酪氨酸酶螯合,因此具有亮肤特性。曲酸也常用作普通化妆品、漂白化妆品等中的增白剂。它是一种治疗剂,有助于防止色素沉着。
应用
曲酸可用作分析参考标准品,用于通过高效液相色谱紫外检测(HPLC-UV)测定皮肤增白化妆品和漂泊化妆品中的分析物。
有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务部门。
生化/生理作用
酪氨酸酶抑制剂。
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储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Simultaneous determination of magnesium ascorbyl phosphate, ascorbyl glucoside, kojic acid, arbutin and hydroquinone in skin whitening cosmetics by HPLC
Huang C-S, et al.
Journal of food and drug analysis, 12(1) (2004)
Combining high-performance liquid chromatography with on-line microdialysis sampling for the simultaneous determination of ascorbyl glucoside, kojic acid, and niacinamide in bleaching cosmetics.
Lin CH et al
Analytica Chimica Acta, 581(1), 102-107 (2007)
Min Hi Park et al.
Archives of pharmacal research, 38(4), 505-511 (2014-12-17)
Tyrosinase inhibitors might have potential use in cosmetic and medicinal products for the prevention of pigmentation disorders. However, only a few inhibitors are currently used due to their cytotoxicity, and lack of selectivity and stability. In this study, we synthesized
Quantitative determination of $\alpha$-arbutin, $\beta$-arbutin, kojic acid, nicotinamide, hydroquinone, resorcinol, 4-methoxyphenol, 4-ethoxyphenol, and ascorbic acid from skin whitening products by HPLC-UV
Wang YH, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 98(1), 5-12 (2015)
Atsushi Yoshimori et al.
Bioorganic & medicinal chemistry, 22(21), 6193-6200 (2014-10-08)
Tyrosinase inhibitors have become increasingly critical agents in cosmetic, agricultural, and medicinal products. Although a large number of tyrosinase inhibitors have been reported, almost all the inhibitors were unfortunately evaluated by using commercial available mushroom tyrosinase. Here, we examined the
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