推荐产品
等级
analytical standard
质量水平
蒸汽压
0.8 mmHg ( 20 °C)
检测方案
≥99.0% (GC)
保质期
limited shelf life, expiry date on the label
expl. lim.
14 %
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤3.0% water
bp
145-146 °C (lit.)
mp
109-112 °C (lit.)
溶解性
H2O: 0.9 g/L at 20 °C
应用
cleaning products
cosmetics
flavors and fragrances
food and beverages
forensics and toxicology
personal care
veterinary
格式
neat
SMILES字符串
C1CNCCN1
InChI
1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2
InChI key
GLUUGHFHXGJENI-UHFFFAOYSA-N
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一般描述
哌嗪是一种驱虫药，可用于治疗哺乳动物和鸟类的蛔虫病和小肠蠕虫病。
应用
哌嗪可作为参考标准品，通过亲水作用色谱和蒸发光散射检测法，对药物制剂中的哌嗪进行测定。
有关合适的仪器技术的更多信息，请参阅产品的分析证书。想要获得更多支持，请联系技术服务部。
警示用语：
Danger
危险分类
Eye Dam. 1 - Flam. Sol. 1 - Repr. 2 - Resp. Sens. 1B - Skin Corr. 1B - Skin Sens. 1B
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
危险化学品
Novel method for the determination of piperazine in pharmaceutical drug substances using hydrophilic interaction chromatography and evaporative light scattering detection.
McClintic C, et al.
Journal of Liquid Chromatography and Related Technologies, 26(18), 3093-3104 (2003)
R A Lovell
The Veterinary clinics of North America. Small animal practice, 20(2), 453-468 (1990-03-01)
Review of all reports involving anthelmintics in dogs and cats to the IAPIC between January 1, 1986 and August 10, 1988, revealed that ivermectin (extra-label use) and piperazine accounted for over 50% of the calls assessed as toxicoses and suspected
Janie Sheridan et al.
Drug and alcohol review, 26(3), 335-343 (2007-04-25)
In this Harm Reduction Digest Sheridan, Butler, Wilkins and Russell address the emergent phenomenon of so-called 'legal party pills' which have become a significant drug issue in New Zealand and elsewhere. Although banned in a number of countries, they are
Rahul V Patel et al.
Mini reviews in medicinal chemistry, 13(11), 1579-1601 (2013-07-31)
This article purposes to provide insights to piperazine based molecular designs that will facilitate drug discovery program in future. In our pursuit to summarize the reservoir of bioactive agents, and in line with the synthetic economy of new heterocycles, many
Julio H K Rozenfeld et al.
Biochimica et biophysica acta, 1848(1 Pt A), 127-133 (2014-10-16)
In this work, the bilayer structure of novel cationic lipid diC16-amidine was compared to the one of zwitterionic dipalmitoyl phosphatidylcholine ( DPPC), which shares the same hydrophobic domain. Differential scanning calorimetry shows that DPPC and diC16-am idine bilayers have similar
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