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Merck
CN

92688

Supelco

5,5-二甲基-1-吡咯啉-N-氧化物

for ESR-spectroscopy

别名:

DMPO

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About This Item

经验公式(希尔记法):
C6H11NO
CAS号:
分子量:
113.16
Beilstein:
107603
EC 号:
MDL编号:
UNSPSC代码:
12000000
PubChem化学物质编号:
NACRES:
NA.21

等级

for ESR-spectroscopy

质量水平

方案

≥98.0% (GC)

表单

crystals

折射率

n20/D 1.496 (lit.)

沸点

75 °C/0.4 mmHg (lit.)

mp

25-29 °C (lit.)

密度

1.015 g/mL at 25 °C (lit.)

储存温度

−20°C

SMILES字符串

CC1(C)CCC=[N+]1[O-]

InChI

1S/C6H11NO/c1-6(2)4-3-5-7(6)8/h5H,3-4H2,1-2H3

InChI key

VCUVETGKTILCLC-UHFFFAOYSA-N

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应用

5,5-二甲基-1-吡咯啉-N-氧化物是在吡咯烷衍生物的合成过程中通常用作自由基自旋捕获剂或亲电子组分的试剂。它也被认为是环加成过程中的1,3-偶极子。
神经保护剂;一氧化氮自旋捕获剂。用于研究通过酶促乙醛氧化反应形成的自由基。
神经保护剂;一氧化氮自旋捕获剂。用于研究通过酶促乙醛氧化反应形成的自由基。用DMPO孵育淋巴细胞,可减少NiCl2对DNA的损伤。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

203.0 °F - closed cup

闪点(°C)

95 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sambuddha Banerjee et al.
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We compared oxygenation and anaerobic oxidation reactions of a purified complex of human hemoglobin (Hb) and haptoglobin (Hb-Hp) to those of uncomplexed Hb. Under equilibrium conditions, Hb-Hp exhibited active-site heterogeneity and noncooperative, high-affinity O(2) binding (n(1/2)=0.88, P(1/2)=0.33 mm Hg in
Murugesan Velayutham et al.
Free radical biology & medicine, 51(1), 160-170 (2011-05-07)
In cells, mitochondria, endoplasmic reticulum, and peroxisomes are the major sources of reactive oxygen species (ROS) under physiological and pathophysiological conditions. Cytochrome c (cyt c) is known to participate in mitochondrial electron transport and has antioxidant and peroxidase activities. Under
Karim Michail et al.
Analytical chemistry, 84(15), 6739-6746 (2012-06-26)
Free radicals are conventionally detected by electron paramagnetic resonance (EPR) spectroscopy after being trapped as spin adducts. Albeit this technique has demonstrated utmost efficacy in studying free radicals, its application to biological settings is intrinsically hampered by the inevitable bioreduction
Ronald P Mason
Free radical biology & medicine, 36(10), 1214-1223 (2004-04-28)
The detection of protein free radicals using the specific free radical reactivity of nitrone spin traps in conjunction with nitrone-antibody sensitivity and specificity greatly expands the utility of the spin trapping technique, which is no longer dependent on the quantum
Pedro L Zamora et al.
The journal of physical chemistry. A, 116(26), 7210-7218 (2012-06-07)
Radical forms of sulfur dioxide (SO(2)), sulfite (SO(3)(2-)), sulfate (SO(4)(2-)), and their conjugate acids are known to be generated in vivo through various chemical and biochemical pathways. Oxides of sulfur are environmentally pervasive compounds and are associated with a number

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