92600
川陈皮素
analytical standard
别名:
2-（3,4-二羟基苯基）-5,6,7,8-三羟基-4 H -1-苯并吡喃-4-酮, 3′,4′,5,6,7,8-六甲氧基黄酮
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关于此项目
经验公式（希尔记法）:
C21H22O8
化学文摘社编号:
分子量:
402.39
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
360887
InChI key
MRIAQLRQZPPODS-UHFFFAOYSA-N
SMILES string
COc1ccc(cc1OC)C2=CC(=O)c3c(OC)c(OC)c(OC)c(OC)c3O2
InChI
1S/C21H22O8/c1-23-13-8-7-11(9-15(13)24-2)14-10-12(22)16-17(25-3)19(26-4)21(28-6)20(27-5)18(16)29-14/h7-10H,1-6H3
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤5.0% water
application(s)
food and beverages
format
neat
Quality Level
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Application
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Biochem/physiol Actions
川陈皮素可抑制基质金属蛋白酶1、3和9的表达，这些酶参与肿瘤转移过程中细胞外基质的分解。 川陈皮素还可增加基质金属蛋白酶1组织抑制剂的表达，从而进一步阻止肿瘤侵袭过程中细胞外基质降解。 这种生物类黄酮通过破坏Ras-Raf-MEK信号转导途径来实现这两种功能。
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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