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等级
analytical standard
质量水平
方案
≥97% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
food and beverages
包装形式
neat
储存温度
2-8°C
SMILES字符串
Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O
InChI
1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H
InChI key
TZBJGXHYKVUXJN-UHFFFAOYSA-N
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一般描述
Genistein是一种天然存在的大豆异黄酮，是一种饮食蛋白酪氨酸激酶(PTK抑制剂。目前发现它具有抗癌特性。
应用
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
生化/生理作用
酪氨酸蛋白激酶抑制剂; 在其他蛋白激酶反应中，ATP的竞争性抑制剂。 抗血管生成剂，可下调参与控制血管生成的基因的转录。
包装
无底玻璃瓶。内含物在插入的融合锥体内。
其他说明
This compound is commonly found in plants of the genus: glycyrrhiza
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Alexandra Mamagkaki et al.
PloS one, 16(4), e0250599-e0250599 (2021-04-28)
The objective of this study is to improve and optimize the formulation of Genistein in capsules in order to result in a better pharmacokinetic profile comparing to existing commercial products. In order to do this, five different formulations of Genistein
Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells
GP and SB
Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research, 7, 1345-1351 (1996)
Genistein inhibits renal cancer progression through long non-coding RNA HOTAIR suppression
Imai-Sumida M, et al.
Clinical Cancer Research, 3449-3449 (2017)
Sonia de Pascual-Teresa et al.
The Journal of nutritional biochemistry, 17(4), 257-264 (2005-08-20)
If soy isoflavones are to be effective in preventing or treating a range of diseases, they must be bioavailable, and thus understanding factors which may alter their bioavailability needs to be elucidated. However, to date there is little information on
Determination of lignans and isoflavonoids in human female plasma following dietary supplementation.
M S Morton et al.
The Journal of endocrinology, 142(2), 251-259 (1994-08-01)
Plasma levels of the lignans enterodiol and enterolactone, and also the isoflavonic phyto-oestrogens daidzein, equol and genistein, are reported for postmenopausal Australian women consuming a traditional diet supplemented with linseed, soya flour or clover sprouts. Analysis was performed by gas
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