跳转至内容
Merck
CN
所有图片(2)

文件

安全信息

917605

Sigma-Aldrich

2-(4-(Piperidin-4-yl)phenyl)acetic acid hydrochloride

≥95%

别名:

Semi-flexible linker for PROTAC® development

登录查看公司和协议定价
所有图片(2)

About This Item

经验公式（希尔记法）:
C13H18ClNO2
CAS号:
34033-52-8
分子量:
255.74
UNSPSC代码:
12352106
NACRES:
NA.22

质量水平

100

检测方案

≥95%

形式

powder

反应适用性

reagent type: linker

官能团

carboxylic acid

储存温度

2-8°C

SMILES字符串

O=C(CC(C=C1)=CC=C1C2CCNCC2)O.Cl

相关类别

应用

2-(4-(Piperidin-4-yl)phenyl)acetic acid hydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.

其他说明

Portal: Building PROTAC® Degraders for Targeted Protein Degradation

Crosslinkers for Bioconjugation

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

相关产品

产品编号
说明
价格

917362

2-(4-(1-(tert-butoxycarbonyl)piperidin-4-yl)phenyl)acetic acid, ≥95%

917125

tert-Butyl 4-(4-(hydroxymethyl)phenyl)piperidine-1-carboxylate, ≥95%

917109

2-(3-(1-(tert-butoxycarbonyl)piperidin-4-yl)phenyl)acetic acid

917869

2-(2-(Piperidin-4-yl)phenyl)acetic acid hydrochloride, ≥95%

916870

4-(1-(tert-butoxycarbonyl)piperidin-4-yl)benzoic acid, ≥95%

916617

2-(3-(Piperidin-4-yl)phenyl)acetic acid hydrochloride, ≥95%

916633

(3-(Piperidin-4-yl)phenyl)methanamine dihydrochloride, ≥95%

917591

tert-Butyl 4-(3-(2-hydroxyethyl)phenyl)piperidine-1-carboxylate, ≥95%

916889

tert-Butyl 4-(4-(2-aminoethyl)phenyl)piperidine-1-carboxylate, ≥95%

916900

2-(3-(Piperidin-4-yl)phenyl)ethan-1-ol hydrochloride, ≥95%

916641

2-(3-(Piperidin-4-yl)phenyl)ethan-1-amine dihydrochloride, 95%

917648

(4-(Piperidin-4-yl)phenyl)methanol hydrochloride, ≥95%

916854

2-(Piperidin-4-yl)benzoic acid hydrochloride, 95%

917907

2-(4-(Piperidin-4-yl)phenyl)ethan-1-amine dihydrochloride, ≥95%

917095

4-(Piperidin-4-yl)benzoic acid hydrochloride, ≥95%

917893

(2-(Piperidin-4-yl)phenyl)methanol hydrochloride, ≥95%

917656

3-(Piperidin-4-yl)benzoic acid hydrochloride, ≥95%

917168

tert-Butyl 4-(2-(hydroxymethyl)phenyl)piperidine-1-carboxylate, ≥95%

917397

(2-(Piperidin-4-yl)phenyl)methanamine dihydrochloride

917419

2-(2-(Piperidin-4-yl)phenyl)ethan-1-amine dihydrochloride

917354

tert-Butyl 4-(4-(aminomethyl)phenyl)piperidine-1-carboxylate

917141

2-(4-(Piperidin-4-yl)phenyl)ethan-1-ol hydrochloride, ≥95%

916625

tert-Butyl 4-(3-(2-aminoethyl)phenyl)piperidine-1-carboxylate, ≥95%

917915

2-(2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)phenyl)acetic acid, ≥95%

917133

(4-(Piperidin-4-yl)phenyl)methanamine dihydrochloride, ≥95%

917400

tert-Butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate, ≥95%

917664

2-(2-(Piperidin-4-yl)phenyl)ethan-1-ol hydrochloride, ≥95%

916897

(3-(Piperidin-4-yl)phenyl)methanol hydrochloride, ≥95%

916846

2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)benzoic acid, 95%

916595

tert-Butyl 4-(4-(2-hydroxyethyl)phenyl)piperidine-1-carboxylate, ≥95%

916587

3-(1-(tert-Butoxycarbonyl)piperidin-4-yl)benzoic acid, ≥95%

917850

tert-Butyl 4-(2-(2-hydroxyethyl)phenyl)piperidine-1-carboxylate, ≥95%

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门