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Merck
CN

91443

Supelco

甘草酸 铵盐

analytical standard, suitable for HPLC

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经验公式(希尔记法):
C42H62O16 · NH3
CAS号:
分子量:
839.96
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

检测方案

≥90.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

格式

neat

SMILES字符串

N.CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]3(C)[C@@H]2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@@]34C)C(O)=O)O[C@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)C(O)=O)C(O)=O

InChI

1S/C42H62O16.H3N/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50;/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54);1H3/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+;/m0./s1

InChI key

ILRKKHJEINIICQ-OOFFSTKBSA-N

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应用

Glycyrrhizic acid ammonium salt may be used as a primary chemical reference standard for the quantitative determination of glycyrrhizic acid in Glycyrrhiza uralensis fisch. ex DC. plant root using high performance liquid chromatography(HPLC).
Glycyrrhizic acid ammonium salt may be used as an analytical standard for the determination of glycyrrhizic acid in biological fluids using micellar electrokinetic chromatographic technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

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象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

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The determination of glycyrrhizic acid in Glycyrrhiza uralensis Fisch. ex DC.(Zhi Gan Cao) root and the dried aqueous extract by LC?DAD
Hennell.R.J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 47, 494-500 (2008)
Determination of glycyrrhizic acid and 18-β-glycyrrhetinic acid in biological fluids by micellar electrokinetic chromatography
Wang P, et al.
Journal of Chromatography A, 811(1-2), 219-224 (1998)
Yu Okuma et al.
Neuropharmacology, 85, 18-26 (2014-05-27)
Glycyrrhizin (GL) is a major constituent of licorice root and has been suggested to inhibit the release of high mobility group box-1 (HMGB1), a protein considered representative of damage-associated molecular patterns. We found that GL bound HMGB1 but not RAGE
Chiung-Hung Chang et al.
PloS one, 9(8), e105362-e105362 (2014-08-19)
Salmonella, a common zoonotic pathogen, causes gastroenteritis in both humans and animals. Traditional Chinese Medicine (TCM) has been used to improve gastrointestinal dysfunction and to modify the immune response to inflammation for centuries. This study used six herbal plants and
Pil-Sung Yang et al.
Respiratory research, 15, 148-148 (2014-11-26)
High mobility group box-1 (HMGB1), a proinflammatory cytokine, plays a pivotal role in tissue remodeling and angiogenesis, both of which are crucial for the pathogenesis of pulmonary arterial hypertension. In this study, we explored the relationship between HMGB1 and pulmonary

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