所有图片(2)
别名:
1,6-二氯-1,6-二脱氧 - ＆＃946;-D呋喃果糖基-4-氯-4-脱氧 - ＆＃945;-D-吡喃半乳糖苷, E955, 三氯蔗糖
经验公式（希尔记法）:
C12H19Cl3O8
CAS号:
分子量:
397.63
Beilstein:
3654410
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
E编号:
E955
NACRES:
NA.24
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等级
analytical standard
质量水平
检测方案
≥98.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
cleaning products
cosmetics
food and beverages
personal care
格式
neat
SMILES字符串
OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl
InChI
1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1
InChI key
BAQAVOSOZGMPRM-QBMZZYIRSA-N
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一般描述
Sucralose is a derivative of sucrose, which is generally used as a non-nutritive sweetener in foods and beverages.
Sucralose, belonging to the class of synthetic sweeteners, is a noncarcinogenic taste enhancer, found to be 400-800 times sweeter than sucrose. It is not involved in inducing glycemic response and is virtually noncaloric. Sucralose is used as a part of a comprehensive portfolio of analytical standards to monitor natural and artificial sugar substitutes in the food and beverage industries. This product finds applications as a sweetener in a variety of food products and beverages including desserts, bakery products, canned fruits/vegetables, dressings, breakfast cereals, confectionery, medical foods, dietary supplements, etc.
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sucralose may be used as an analytical reference standard for the quantification of the analyte in:
- Commercial sugar-free products such as Splenda and Red Raspberry Diet Rite beverage using high performance anion-exchange (HPAE) chromatography coupled with pulsed amperometric detection (PAD).
- Water and beverage samples using liquid chromatography/time-of-flight mass spectrometry (LC/TOF-MS).
生化/生理作用
一种人类可以检测到的合成甜味剂。可激活肠内分泌细胞上的 T1R2/T1R3 甜味受体，引起胰高血糖素样肽-1 和葡萄糖依赖性胰岛素肽的激素分泌增加。
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Food Analysis by HPLC, Second Edition (2000)
An overview of the safety of sucralose
Grotz L.V and Munro C.I
Regulatory Toxicology and Pharmacology, 55(01), 1-5 (2009)
Mitchell.AE et al.
Formulation and Production Carbonated Soft Drinks (1990)
Determination of sucralose in splenda and a sugar-free beverage using high-performance anion-exchange chromatography with pulsed amperometric detection
Hanko PV, et al.
Journal of Agricultural and Food Chemistry, 52(14), 4375-4379 (2004)
Christopher B Forsyth et al.
PloS one, 6(12), e28032-e28032 (2011-12-07)
Parkinson's disease (PD) is the second most common neurodegenerative disorder of aging. The pathological hallmark of PD is neuronal inclusions termed Lewy bodies whose main component is alpha-synuclein protein. The finding of these Lewy bodies in the intestinal enteric nerves
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