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Merck
CN

90957

Swertiamarin

analytical standard

别名:

(4aR,5R,6S)-5-Ethenyl-6-(β-D-glucopyranosyloxy)-4,4a,5,6-tetrahydro-4a-hydroxy1H,3H-pyrano[3,4-c]pyran-1-one, 4,4a,5,6-Tetrahydro-4aα-hydroxy-1-oxo-5β-vinyl-1H,3H-pyrano[3,4-c]pyran-6-yl β-D-glucopyranoside, Swertiamarine, Swertiamaroside

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关于此项目

经验公式（希尔记法）:
C16H22O10
化学文摘社编号:
17388-39-5
分子量:
374.34
UNSPSC Code:
85151701
PubChem Substance ID:
329769972
NACRES:
NA.24
Beilstein/REAXYS Number:
55278
MDL number:
MFCD07783984

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SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@@H]2OC=C3[C@]([C@H]2C=C)(CCOC3=O)O

InChI key

HEYZWPRKKUGDCR-QBXMEVCASA-N

InChI

1S/C16H22O10/c1-2-7-14(24-6-8-13(21)23-4-3-16(7,8)22)26-15-12(20)11(19)10(18)9(5-17)25-15/h2,6-7,9-12,14-15,17-20,22H,1,3-5H2/t7-,9+,10+,11-,12+,14-,15-,16+/m0/s1

grade

analytical standard

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

Quality Level

100

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相关类别

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN8503
BCCK3666
BCCG5741
BCCC7195
BCCB3496

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V Jaishree et al.
Journal of ethnopharmacology, 130(1), 103-106 (2010-04-28)
The whole plant of Enicostemma axillare Raynal (Family: Gentianaceae) is used in variety of diseases in traditional Indian system of medicine including hepatic ailments. Swertiamarin isolated from Enicostemma axillare Raynal was evaluated for antioxidant and hepatoprotective activity. Swertiamarin was isolated
M B Patel et al.
Pharmaceutical biology, 49(4), 383-391 (2011-03-12)
Enicostemma hyssopifolium Verdoon (Gentianaceae) has been documented for various therapeutic effects in traditional systems of medicine; the hypoglycemic and hypolipidemic activities are also well reported. Bioactivity guided fractionation of methanol extract of E. hyssopifolium to test the hypothesis that E.
H-L Li et al.
Arzneimittel-Forschung, 62(3), 138-144 (2012-01-27)
An LC-MS/MS method was developed for the quantification of swertiamarin (CAS 17388-39-5) in rat plasma and tissues using gentiopicroside as the internal standard (IS). Swertiamarin and an IS were extracted from plasma and tissues by a simple solid-phase extraction (SPE)
Rakesh D Sonawane et al.
Molecular and cellular biochemistry, 340(1-2), 1-6 (2010-03-17)
Diabetic nephropathy (DN) is one of the foremost causes of renal failure and a primary cause of diabetes mellitus related death. Previously, we have reported that aqueous extract of Enicostemma littorale has potential antidiabetic activity. In the present study, we
Kangping Xu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 34(11), 1384-1389 (2009-09-24)
To develop an HPLC method for the quantification of six active components in three species (Swertia davidi, S. nervosa and S. mussotii) . The determination was performed on a Hypersil BDS colunm (4. 6 mm x 200 mm, 5 microm).
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