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等级
analytical standard
质量水平
检测方案
≥95% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
food and beverages
格式
neat
SMILES字符串
C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](C\C=C3/[C@H](O)COC3=O)C(=C)CC[C@H]12
InChI
1S/C20H30O5/c1-12-4-7-16-19(2,9-8-17(23)20(16,3)11-21)14(12)6-5-13-15(22)10-25-18(13)24/h5,14-17,21-23H,1,4,6-11H2,2-3H3/b13-5+/t14-,15-,16+,17-,19+,20+/m1/s1
InChI key
BOJKULTULYSRAS-OTESTREVSA-N
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一般描述
Andrographolide is a major bioactive component of Andrographis paniculata Nees. which is a popular Chinese and Indian medicine. It belongs to the terpenoid class of compounds.
应用
Andrographolide may be used as a reference standard for the determination of andrographolide in:
- Leaves of Andrographis paniculata by soxhlet extraction-recrystallization-column chromatography purification followed by analyses using reversed phase high performance liquid chromatography (RP-HPLC) as well as gas chromatography-mass spectrometry (GC-MS).
- Roots of Andrographis paniculata by HPLC with diode array detection (DAD), gas chromatography-mass spectrometry (GC-MS) and LC coupled to tandem mass spectrometry (MS/MS) equipped with electrospray ionization (ESI) and multiple reaction monitoring (MRM) mode of detection.
- Stems of Andrographis paniculata by ultra-HPLC combined coupled to triple quadrupole-linear ion trap mass spectrometry (QqQLIT-ESI-MS/MS) with MRM detection.
- Rat plasma samples by protein precipitation and subsequent ESI-LC-MS/MS determination using MRM detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Determination of six components of Andrographis paniculata extract and one major metabolite of andrographolide in rat plasma by liquid chromatography-tandem mass spectrometry
Journal of Chromatography. B, Biomedical Sciences and Applications, 951(2), 78-88 (2014)
In vitro metabolism of sodium 9-dehydro-17-hydro-andrographolide-19-yl sulfate in rat liver s9 by liquid chromatography-mass spectrometry method.
Pharmacognosy magazine, 12(2), S102-S102 (2016)
Rapid quantitative analysis of multi-components in Andrographis paniculata using UPLC-QqQLIT-MS/MS: Application to soil sodicity and organic farming.
Industrial Crops and Products, 83(2), 423-430 (2016)
Determination of phytochemicals, antioxidant activity and total phenolic content in Andrographis paniculata using chromatographic methods.
Journal of Chromatography. B, Biomedical Sciences and Applications, 995(2), 101-106 (2015)
Anti-dengue efficacy of bioactive andrographolide from Andrographis paniculata (Lamiales: Acanthaceae) against the primary dengue vector Aedes aegypti (Diptera: Culicidae).
Acta Tropica, 163(2), 167-178 (2016)
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