等级
analytical standard
质量水平
检测方案
≥97.0% (HPLC)
旋光性
[α]1.15/D -0.5±0.5° in chloroform
保质期
limited shelf life, expiry date on the label
药品控制
USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
clinical testing
格式
neat
官能团
ketone
储存温度
2-8°C
SMILES字符串
C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C20H28O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h6,9,12,15-17,22H,4-5,7-8,10-11H2,1-3H3/t15-,16+,17+,18+,19+,20+/m1/s1
InChI key
XWALNWXLMVGSFR-HLXURNFRSA-N
基因信息
human ... AR(367)
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一般描述
17β-hydroxy-17-methylandrosta-1,4-dien-3-one is an androgenic anabolic steroid.
应用
17β-hydroxy-17-methylandrosta-1,4-dien-3-one may be used as a reference standard in the determination of 17β-hydroxy-17-methylandrosta-1,4-dien-3-one in urine samples, using by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Comparative study of matrices for their use in the rapid screening of anabolic steroids by matrix?assisted laser desorption/ionisation time?of?flight mass spectrometry
Galesio.M, et al.
Rapid Communications in Mass Spectrometry, 23, 1783-1791 (2009)
Stephanie Mosler et al.
Archives of toxicology, 86(1), 109-119 (2011-08-06)
There is increasing evidence that the biological activity of myostatin (MSTN), a negative regulator of muscle growth, is affected by training but also anabolic steroids. In this study, we analyzed the effects of the frequently abused anabolic steroid methandienone (Md)
Andy Zöllner et al.
Biological chemistry, 391(1), 119-127 (2009-11-19)
Anabolic-androgenic steroids are some of the most frequently misused drugs in human sports. Recently, a previously unknown urinary metabolite of metandienone, 17beta-hydroxymethyl-17 alpha-methyl-18-norandrosta-1,4,13-trien-3-one (20OH-NorMD), was discovered via LC-MS/MS and GC-MS. This metabolite was reported to be detected in urine samples
Oscar J Pozo et al.
Drug testing and analysis, 1(11-12), 554-567 (2010-04-01)
Anabolic steroids are among the most frequently detected compounds in doping analysis. They are extensively metabolized and therefore an in-depth knowledge about steroid metabolism is needed. In this study, a liquid chromatography tandem mass spectometry (LC-MS/MS) method based on a
Yun Wang et al.
International journal of biological macromolecules, 49(3), 428-432 (2011-06-15)
The development of a chitosan-supported immunoaffinity chromatography (IAC) column and its application to the selective extraction of methandrostenolone (MA) from food and feed samples were described in this paper. Using hybridoma technique, a monoclonal antibody (mAb) against MA was produced.
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