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Merck
CN

88580

Sigma-Aldrich

吩噻嗪

purum, ≥98.0% (GC)

别名:

10H-吩噻嗪

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About This Item

经验公式(希尔记法):
C12H9NS
CAS号:
分子量:
199.27
Beilstein:
143237
EC 号:
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.23
方案:
≥98.0% (GC)
沸点:
371 °C (lit.)

等级

purum

质量水平

方案

≥98.0% (GC)

表单

pellets

沸点

371 °C (lit.)

mp

182-187 °C (lit.)
183-187 °C

SMILES字符串

N1c2ccccc2Sc3ccccc13

InChI

1S/C12H9NS/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H

InChI key

WJFKNYWRSNBZNX-UHFFFAOYSA-N

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一般描述

吩噻嗪为刚性、三环结构。已知其可改变多巴胺(3,4-二羟基苯乙胺)。其独特的空穴输运能力、电子释放氮和硫的杂原子以及其非平面结构导致较低的分子聚集,使其可作为电子供体。

应用

吩噻嗪在无金属的有机染料敏化剂、染料 和抗氧化剂中都有应用。

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT RE 2 Oral

靶器官

Blood

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A S Horn et al.
Proceedings of the National Academy of Sciences of the United States of America, 68(10), 2325-2328 (1971-10-01)
Phenothiazines and butyrophenones are known to alter dopamine (3,4-dihydroxyphenethylamine) metabolism in the brain in a fashion suggesting that they may block dopamine receptors. We observed, using Dreiding molecular models, that dopamine in its solid-state conformation is superimposable upon a portion
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease
Carsten K, et al
Proceedings of the National Academy of Sciences of the USA, 98(17), 9834-9841 (2001)
Asif M, et al
Arabian Journal of Chemistry null
Photodegradation of trimeprazine triggered by self-photogenerated singlet molecular oxygen
Waseem A, et al
Journal of Saudi Chemical Society (2012)
Lavinia Baciu-Atudosie et al.
Bioorganic & medicinal chemistry letters, 22(22), 6896-6902 (2012-10-06)
A new family of protein farnesyltransferase inhibitors, based on a phenothiazine scaffold, was designed and synthesized. The biological evaluation of these products showed that compounds 28 and 30 were the most active, with protein farnesyltransferase inhibition potencies in the low

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