推荐产品
等级
for ion-selective electrodes
质量水平
产品线
Selectophore™
方案
≥99.0% (GC)
≥99.0%
表单
liquid
折射率
n20/D 1.490
密度
1.025 g/mL at 20 °C (lit.)
SMILES字符串
CCCCCOC(=O)c1ccccc1C(=O)OCCCCC
InChI
1S/C18H26O4/c1-3-5-9-13-21-17(19)15-11-7-8-12-16(15)18(20)22-14-10-6-4-2/h7-8,11-12H,3-6,9-10,13-14H2,1-2H3
InChI key
IPKKHRVROFYTEK-UHFFFAOYSA-N
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一般描述
Dipentyl phthalate (DPeP) belongs to phthalate group, and is a dialkyl or aryl/alkyl diesters of phthalic acid. It may be prepared from phthalic anhydride along with n-pentanol.
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应用
- Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats: Dipentyl phthalate′s structural similarities to DINP underpin studies on phthalate exposure′s impacts on male reproductive health, providing insights into potential risks and mechanisms of toxicity in developmental stages (Earl Gray L Jr, 2023).
- Exposure to dipentyl phthalate in utero disrupts the adrenal cortex function of adult male rats by inhibiting SIRT1/PGC-1α and inducing AMPK phosphorylation: This study uses dipentyl phthalate to examine the adverse effects of phthalate exposure on adrenal gland function, contributing to a deeper understanding of metabolic disruptions (Chen et al., 2023).
- Determination of 15 phthalic acid esters based on GC-MS/MS coupled with modified QuEChERS in edible oils: This research demonstrates the utility of dipentyl phthalate in method development for detecting phthalates in food matrices, enhancing food safety assessments (Wang et al., 2022).
- Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development: Dipentyl phthalate is investigated for its role in developmental toxicity, aiding in the construction of models predicting reproductive health effects from chemical exposures (Palermo et al., 2021).
其他说明
用于 PVC 膜电极的增塑剂
法律信息
Selectophore is a trademark of Merck KGaA, Darmstadt, Germany
警示用语:
Danger
危险声明
危险分类
Aquatic Acute 1 - Repr. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
244.4 °F - closed cup
闪点(°C)
118 °C - closed cup
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Analytical Letters, 26, 2071-2071 (1993)
Potassium-selective electrodes based on macrocyclic polyethers: The effect of structure of the neutral carrier on selectivity.
Analytica Chimica Acta, 72.2, 375-380 (1974)
Journal of andrology, 28(4), 621-629 (2007-04-06)
Acute effects of CDB-4022 on testicular ultrastructure were determined. Rats were treated orally with vehicle or a maximally effective single dose of CDB-4022 or Di-n-pentylphthalate (DPP). Preserved testes were processed for transmission electron microscopy. Sertoli and germ cells of vehicle-treated
Toxicology letters, 15(2-3), 265-271 (1983-02-01)
Treatment of young male rats with dipentyl phthalate (DPP) produced significant decreases in testicular cytochrome P-450, cytochrome P-450 dependent microsomal steroidogenic enzymes (17 alpha-hydroxylase, 17-20 lyase) and in the maximal binding of a natural substrate (progesterone) to testis microsomes. No
Journal of reproductive immunology, 21(1), 1-14 (1992-01-01)
Phthalate esters (PAE) are plasticizers in polyvinyl chloride plastics used, for example, in package material for medical solutions. PAE exposure is associated with testicular damage that primarily affects Sertoli cells, and is concomitant with leukocyte infiltration into the testicular interstitium.
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