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Merck
CN

77500

1,10-菲咯啉 一水合物

for the spectrophotometric determination of Fe, Pd, V, ≥99.0%

别名:

邻菲咯啉 一水合物

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关于此项目

经验公式（希尔记法）:
C12H8N2 · H2O
化学文摘社编号:
5144-89-8
分子量:
198.22
UNSPSC Code:
23151817
NACRES:
NA.21
PubChem Substance ID:
329767727
EC Number:
200-629-2
Beilstein/REAXYS Number:
4008096
MDL number:
MFCD00149973

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产品名称

1,10-菲咯啉 一水合物, for the spectrophotometric determination of Fe, Pd, V, ≥99.0%

InChI key

PPQJCISYYXZCAE-UHFFFAOYSA-N

InChI

1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2

SMILES string

O.c1cnc2c(c1)ccc3cccnc23

assay

≥99.0% (HPLC)
≥99.0% (NT)
≥99.0%

form

crystals

quality

for the spectrophotometric determination of Fe, Pd, V

technique(s)

UV/Vis spectroscopy: suitable
titration: suitable

ign. residue

≤0.05%

mp

100-104 °C (lit.)
99-104 °C

cation traces

Ca: ≤50 mg/kg
Cd: ≤20 mg/kg
Co: ≤20 mg/kg
Cr: ≤20 mg/kg
Cu: ≤20 mg/kg
Fe: ≤20 mg/kg
K: ≤100 mg/kg
Mg: ≤20 mg/kg
Mn: ≤20 mg/kg
Na: ≤100 mg/kg
Ni: ≤20 mg/kg
Pb: ≤20 mg/kg
Zn: ≤20 mg/kg

Quality Level

100

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相关类别

Application

当与铜络合时，具有核酸酶活性，用于研究 DNA-蛋白质相互作用。
It has been used in preparing 0.1 % phenanthroline solution. In another study, 80μl of 1,10-Phenanthroline monohydrate was used along with nanoparticles to measure iron content using colorimetric assay.3 It may be used in the preparation of [Mn(1,10-phen)2(mal)].2H2O.

Biochem/physiol Actions

金属蛋白酶抑制剂;可与铁、锌和其他二价金属形成螯合物。有效浓度 1-10mM。

General description

1,10-Phenanthroline monohydrate is a chelating agent.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

hcodes

H301,H410

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCD5471

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Insights into the mode of action of the anti-Candida activity of 1,10-phenanthroline and its metal chelates.
McCann M
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Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 15, 585-585 (1970)
Generation of magnetic nonviral gene transfer agents and magnetofection in vitro.
Mykhaylyk O
Nature Protocols, 2(10), 2391-2411 (2007)
Olivia L Lanier et al.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 36(1), 687-701 (2019-07-26)
Background: Magnetic nanoparticles (MNPs) generate heat when exposed to an alternating magnetic field. Consequently, MNPs are used for magnetic fluid hyperthermia (MFH) for cancer treatment, and have been shown to increase the efficacy of chemotherapy and/or radiation treatment in clinical
A newly developed Fe-doped calcium sulfide nanoparticles with magnetic property for cancer hyperthermia.
Wu, Steven Yueh-Hsiu, Ching-Li Tseng, and Feng-Huei Lin.
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