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等级
analytical standard
质量水平
方案
≥98.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤15% water
mp
152-157 °C
154-158 °C (lit.)
应用
cleaning products
cosmetics
environmental
food and beverages
personal care
包装形式
neat
SMILES字符串
Oc1nsc2ccccc12
InChI
1S/C7H5NOS/c9-7-5-3-1-2-4-6(5)10-8-7/h1-4H,(H,8,9)
InChI key
DMSMPAJRVJJAGA-UHFFFAOYSA-N
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一般描述
1,2-苯并异噻唑-3(2H)-酮属于异噻唑啉酮类物质。
免责声明
本品不可用作全球生物杀灭剂法规监管的生物杀灭剂，包括但不限于：美国联邦杀虫剂、杀菌剂和灭鼠剂法(US EPA′s Federal Insecticide Fungicide and Rodenticide Act)、欧盟生物杀灭剂法规(European Biocidal Products Regulation)、加拿大虫害管理监管机构(Canada’s Pest Management Regulatory Agency)、土耳其生物杀灭剂法规(Turkey’s Biocidal Products Regulation)、韩国生物杀灭剂法(Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR))等。
免责声明
本品不可用作全球生物杀灭剂法规监管的生物杀灭剂，包括但不限于：美国联邦杀虫剂、杀菌剂和灭鼠剂法(US EPA′s Federal Insecticide Fungicide and Rodenticide Act)、欧盟生物杀灭剂法规(European Biocidal Products Regulation)、加拿大虫害管理监管机构(Canada’s Pest Management Regulatory Agency)、土耳其生物杀灭剂法规(Turkey’s Biocidal Products Regulation)、韩国生物杀灭剂法(Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR))等。
应用
此分析标准品可被用于以下实验：
- 通过液相色谱-串联质谱法（LC-MS/MS）在正电喷雾模式下测定五个土壤样品中的苯并异噻唑啉酮含量
包装
无底玻璃瓶。内含物装在插入式熔锥内。
其他说明
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
警示用语：
Danger
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
农药列管产品
Synthesis and anti-bacterial activity of a library of 1, 2-benzisothiazol-3 (2H)-one (BIT) derivatives amenable of crosslinking to polysaccharides
Viani F, et al.
Tetrahedron, 73(13), 1745-1761 (2017)
Occupational allergic contact dermatitis caused by 1,2-benzisothiazolin-3-one in a varnish maker, followed by sensitization to benzalkonium chloride in Oilatum Plus bath additive.
S L Walker et al.
Contact dermatitis, 50(2), 104-105 (2004-05-07)
William L Jorgensen et al.
Bioorganic & medicinal chemistry letters, 21(15), 4545-4549 (2011-07-02)
Substituted N-phenylbenzisothiazolones have been investigated as inhibitors of the tautomerase activity of the proinflammatory cytokine MIF (macrophage migration inhibitory factor). Numerous compounds were found to possess antagonist activity in the low micromolar range with the most potent being the 6-hydroxy
Alan Rolfe et al.
Journal of combinatorial chemistry, 11(4), 732-738 (2009-06-10)
A sequential three-component synthesis of functionalized benzisothiazoline-3-acetic acid 1,1-dioxides utilizing a domino Heck-aza-Michael pathway is reported. This one-pot procedure rapidly assembles functionalized benzylsulfonamides, which undergo a palladium-catalyzed, domino, Heck-aza-Michael transformation in an experimentally straightforward manner. This attractive protocol has been
Deepu Alex et al.
Antimicrobial agents and chemotherapy, 56(9), 4630-4639 (2012-06-13)
We have identified four synthetic compounds (DFD-VI-15, BD-I-186, DFD-V-49, and DFD-V-66) from an amino acid-derived 1,2-benzisothiazolinone (BZT) scaffold that have reasonable MIC(50) values against a panel of fungal pathogens. These compounds have no structural similarity to existing antifungal drugs. Three
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