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Merck
CN

75110

Supelco

Phyllanthin

analytical standard

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别名:
(2S,3S)-(+)-1,4-Dimethoxy-2,3-diveratrylbutane
经验公式(希尔记法):
C24H34O6
CAS号:
分子量:
418.52
Beilstein:
2066503
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

检测方案

≥95.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

food and beverages

格式

neat

SMILES字符串

COC[C@@H](Cc1ccc(OC)c(OC)c1)[C@@H](COC)Cc2ccc(OC)c(OC)c2

InChI

1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1

InChI key

KFLQGJQSLUYUBF-WOJBJXKFSA-N

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一般描述

Phyllanthin is found in many Phyllanthus species. It is a lignan compound which exhibits various biochemical and pharmacological properties.

应用

Phyllanthin may be used as a reference standard for the determination of the analyte in Phyllanthus species by high-performance thin layer chromatography (HPTLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Protective activity of phyllanthin in ethanol-treated primary culture of rat hepatocytes.
Chirdchupunseree H and Pramyothin P
Journal of Ethnopharmacology, 128(1), 172- 176 (2010)
Quantitative determination of phyllanthin and hypophyllanthin in Phyllanthus species by high-performance thin layer chromatography.
Tripathi AK, et al.
Phytochemical Analysis, 17(6), 394- 397 (2006)
Phyllanthin from Phyllanthus amarus inhibits cellular and humoral immune responses in Balb/C mice.
Ilangkovan M, et al.
Phytomedicine, 23(12), 1441- 1450 (2016)
Cong Zhao et al.
Environmental toxicology (2020-08-17)
Ischemic heart disease is an imperative cause of high morbidity and mortality globally. The cardiac ischemia/reperfusion damage occur in both reperfusion and ischemia. In this exploration, we have planned to examine the cardio-protective action of phyllanthin against the myocardial ischemic-reperfusion
Nguyen Duc Hanh et al.
Drug development and industrial pharmacy, 40(6), 793-802 (2013-04-19)
Phyllanthin is a major bioactive lignan component of Phyllanthus amarus, with several known biological activities. This study dealt with the isolation and physicochemical characterization of phyllanthin. Phyllanthin was isolated from P. amarus leaves by column chromatography and purified by recrystallization

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