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Merck
CN

74777

黄芪甲苷IV

>98.0%

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关于此项目

经验公式(希尔记法):
C41H68O14
化学文摘社编号:
分子量:
784.97
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
41106200
MDL number:
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产品名称

黄芪甲苷IV, >98.0%

InChI

1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1

SMILES string

CC(C)(O)[C@@H]1CC[C@@](C)(O1)[C@H]2[C@@H](O)C[C@@]3(C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H]6C(C)(C)[C@H](CC[C@@]67C[C@@]47CC[C@]23C)O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O

InChI key

QMNWISYXSJWHRY-YLNUDOOFSA-N

assay

≥98.0% (TLC)
>98.0%

form

powder

mp

295-296 °C (lit.)

Quality Level

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Biochem/physiol Actions

抗炎。

Other Notes

黄芪的化学成分

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Dexin Li et al.
Pharmaceutical biology, 58(1), 89-97 (2020-01-08)
Context: Osteoarthritis (OA) is a degenerative arthrosis sickness. Astragaloside IV (AS-IV) functions by relieving inflammatory damage.Objective: We aimed to investigate the mechanism by which AS-IV protects ATD cells from lipopolysaccharide (LPS)-induced damage.Materials and methods: ATDC5 cells were transfected with miR-203
Chemical & Pharmaceutical Bulletin, 31, 709-709 (1983)
Xiaoyan Gu et al.
Molecular medicine reports, 6(1), 115-120 (2012-04-17)
Astragaloside IV (AS-IV) has been noted for its reduction of eosinophilic airway inflammation in a murine model of chronic asthma. To gain a better understanding of the mechanisms involved in this anti-inflammatory phenomenon, the effect of AS-IV on human blood
Rui-Na Zhou et al.
Drug metabolism and pharmacokinetics, 27(6), 586-597 (2012-06-08)
Astragaloside IV (AIV) is the most abundant saponin and a marker compound in Astragali Radix, a Chinese herb notable for its anti-aging and immune-enhancing effects. The present study investigated the role of intestinal bacterial conversion in the in vivo fate
Li-Hua Peng et al.
Biological & pharmaceutical bulletin, 35(6), 881-888 (2012-06-13)
Topical delivery of therapeutic agents at the time of injury to accelerate skin repair and prevent the formation of scars during the wound healing process has received increasing attention and represents a novel regenerative and prophylactic strategy for wound treatment.

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