InChI key
DRBHTUDHPPBMCD-UHFFFAOYSA-M
InChI
1S/C26H38N3.BrH/c1-6-7-8-9-10-11-12-17-29-25-19-23(27(2)3)15-13-21(25)18-22-14-16-24(28(4)5)20-26(22)29;/h13-16,18-20H,6-12,17H2,1-5H3;1H/q+1;/p-1
SMILES string
[Br-].CCCCCCCCC[n+]1c2cc(ccc2cc3ccc(cc13)N(C)C)N(C)C
assay
≥90% (HPLC)
mp
≥250 °C (lit.)
solubility
DMSO: soluble, ethanol, DMSO: soluble, ethanol: soluble, methanol: soluble
fluorescence
λex 494 nm; λem 519 nm in methanol
suitability
suitable for fluorescence
storage temp.
2-8°C
Application
异染色染料可用作活细胞线粒体探针。该染料已用于通过流式细胞术分析线粒体、表征多药耐药性以及检测大鼠胸腺细胞凋亡过程中线粒体质量的变化。
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Fluorescent probe for the in situ study of mitochondria
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
A Maftah et al.
FEBS letters, 260(2), 236-240 (1990-01-29)
The fluorescent dye 10-N-nonyl acridine orange (NAO), known as specifically associated with mitochondria, has been reported to have a cytotoxic effect when high doses were applied to cells. Presently, the biochemical basis of its toxicity was investigated on isolated rat
M H Ratinaud et al.
Cytometry, 9(3), 206-212 (1988-05-01)
Due to its spectral characteristics, the fluorochrome nonyl acridine orange (NAO) (lambda abs:489 nm, lambda em:525 nm), which is spontaneously incorporated by mitochondria with a high relative specificity, provides a new probe for the in situ study of these organelles
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