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等级
for fluorescence
方案
≥90% (HPLC)
mp
≥250 °C (lit.)
溶解性
DMSO: soluble
ethanol, DMSO: soluble
ethanol: soluble
methanol: soluble
荧光
λex 494 nm; λem 519 nm in methanol
储存温度
2-8°C
SMILES字符串
[Br-].CCCCCCCCC[n+]1c2cc(ccc2cc3ccc(cc13)N(C)C)N(C)C
InChI
1S/C26H38N3.BrH/c1-6-7-8-9-10-11-12-17-29-25-19-23(27(2)3)15-13-21(25)18-22-14-16-24(28(4)5)20-26(22)29;/h13-16,18-20H,6-12,17H2,1-5H3;1H/q+1;/p-1
InChI key
DRBHTUDHPPBMCD-UHFFFAOYSA-M
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应用
异染色染料可用作活细胞线粒体探针。该染料已用于通过流式细胞术分析线粒体、表征多药耐药性以及检测大鼠胸腺细胞凋亡过程中线粒体质量的变化。
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
其他说明
Fluorescent probe for the in situ study of mitochondria
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
A Maftah et al.
FEBS letters, 260(2), 236-240 (1990-01-29)
The fluorescent dye 10-N-nonyl acridine orange (NAO), known as specifically associated with mitochondria, has been reported to have a cytotoxic effect when high doses were applied to cells. Presently, the biochemical basis of its toxicity was investigated on isolated rat
M H Ratinaud et al.
Cytometry, 9(3), 206-212 (1988-05-01)
Due to its spectral characteristics, the fluorochrome nonyl acridine orange (NAO) (lambda abs:489 nm, lambda em:525 nm), which is spontaneously incorporated by mitochondria with a high relative specificity, provides a new probe for the in situ study of these organelles
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