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Merck
CN

74395

Sigma-Aldrich

吖啶橙 10-溴壬烷

for fluorescence, ≥90% (HPLC)

别名:

10-壬基吖啶橙溴化物, 3,6-双(二甲基胺)-10-壬基溴代吖啶

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About This Item

经验公式(希尔记法):
C26H38BrN3
CAS号:
分子量:
472.50
MDL编号:
UNSPSC代码:
12171500

等级

for fluorescence

方案

≥90% (HPLC)

mp

≥250 °C (lit.)

溶解性

DMSO: soluble
ethanol, DMSO: soluble
ethanol: soluble
methanol: soluble

荧光

λex 494 nm; λem 519 nm in methanol

储存温度

2-8°C

SMILES字符串

[Br-].CCCCCCCCC[n+]1c2cc(ccc2cc3ccc(cc13)N(C)C)N(C)C

InChI

1S/C26H38N3.BrH/c1-6-7-8-9-10-11-12-17-29-25-19-23(27(2)3)15-13-21(25)18-22-14-16-24(28(4)5)20-26(22)29;/h13-16,18-20H,6-12,17H2,1-5H3;1H/q+1;/p-1

InChI key

DRBHTUDHPPBMCD-UHFFFAOYSA-M

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应用

异染色染料可用作活细胞线粒体探针。该染料已用于通过流式细胞术分析线粒体、表征多药耐药性以及检测大鼠胸腺细胞凋亡过程中线粒体质量的变化。

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

其他说明

Fluorescent probe for the in situ study of mitochondria

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A Maftah et al.
FEBS letters, 260(2), 236-240 (1990-01-29)
The fluorescent dye 10-N-nonyl acridine orange (NAO), known as specifically associated with mitochondria, has been reported to have a cytotoxic effect when high doses were applied to cells. Presently, the biochemical basis of its toxicity was investigated on isolated rat
M H Ratinaud et al.
Cytometry, 9(3), 206-212 (1988-05-01)
Due to its spectral characteristics, the fluorochrome nonyl acridine orange (NAO) (lambda abs:489 nm, lambda em:525 nm), which is spontaneously incorporated by mitochondria with a high relative specificity, provides a new probe for the in situ study of these organelles

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