所有图片(2)
别名:
5-[N-(2,3-二羟丙基)乙酰氨基]-2,4,6-三碘-N,N′-双(2,3-二羟丙基)异邻苯二甲酰亚胺
经验公式（希尔记法）:
C19H26I3N3O9
CAS号:
分子量:
821.14
Beilstein:
2406632
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
推荐产品
等级
analytical standard
质量水平
检测方案
≥95.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤6.0% water
应用
clinical testing
格式
neat
SMILES字符串
IC1=C(C(NCC(O)CO)=O)C(I)=C(C(NCC(CO)O)=O)C(I)=C1N(CC(CO)O)C(C)=O
InChI
1S/C19H26I3N3O9/c1-8(29)25(4-11(32)7-28)17-15(21)12(18(33)23-2-9(30)5-26)14(20)13(16(17)22)19(34)24-3-10(31)6-27/h9-11,26-28,30-32H,2-7H2,1H3,(H,23,33)(H,24,34)
InChI key
NTHXOOBQLCIOLC-UHFFFAOYSA-N
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一般描述
碘海醇是一种非离子型水溶性造影剂，用作测定肾功能水平的肾小球滤过率（GFR）的参考标记。它可以应用于血管造影和泌尿造影过程。
应用
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
碘海醇可用作内标，用于通过 HPLC-UV 法测定人血浆、血清和尿液样品中的碘海醇。在肾衰竭研究中，它也可以用作模型化合物，通过碘海醇的血浆清除率分析碘海醇对肾小球滤过率（GFR）测量适用性。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Performance of iohexol determination in serum and urine by HPLC: validation, risk and uncertainty assessment.
Cavalier E, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 396(1-2), 80-85 (2008)
Development and validation of an HPLC-UV method for determination of iohexol in human plasma.
Soman R S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 816(1-2), 339-343 (2005)
Human pharmacokinetics of iohexol. A new nonionic contrast medium.
BO, et al.
Investigative Radiology, 18(2), 177-182 (1983)
Iohexol clearance for GFR-determination in renal failure?single or multiple plasma sampling?.
Sterner G, et al.
Nephrology, Dialysis, and Transplantation, 11(3), 521-525 (1996)
Aneliya Parvanova et al.
The lancet. Diabetes & endocrinology, 1(1), 19-27 (2014-03-14)
Effective reduction of albuminuria and blood pressure in patients with type 2 diabetes who have nephropathy is seldom achieved with available treatments. We tested the effects of treatment of such patients with daglutril, a combined endothelin-converting enzyme and neutral endopeptidase
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