74147
碘海醇
analytical standard
别名:
5-[N-(2,3-二羟丙基)乙酰氨基]-2,4,6-三碘-N,N′-双(2,3-二羟丙基)异邻苯二甲酰亚胺
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关于此项目
经验公式（希尔记法）:
C19H26I3N3O9
化学文摘社编号:
分子量:
821.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
266-164-2
Beilstein/REAXYS Number:
2406632
MDL number:
产品名称
碘海醇, analytical standard
InChI key
NTHXOOBQLCIOLC-UHFFFAOYSA-N
InChI
1S/C19H26I3N3O9/c1-8(29)25(4-11(32)7-28)17-15(21)12(18(33)23-2-9(30)5-26)14(20)13(16(17)22)19(34)24-3-10(31)6-27/h9-11,26-28,30-32H,2-7H2,1H3,(H,23,33)(H,24,34)
SMILES string
IC1=C(C(NCC(O)CO)=O)C(I)=C(C(NCC(CO)O)=O)C(I)=C1N(CC(CO)O)C(C)=O
grade
analytical standard
assay
≥95.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
impurities
≤6.0% water
application(s)
clinical testing
format
neat
Quality Level
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Application
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。
碘海醇可用作内标，用于通过 HPLC-UV 法测定人血浆、血清和尿液样品中的碘海醇。在肾衰竭研究中，它也可以用作模型化合物，通过碘海醇的血浆清除率分析碘海醇对肾小球滤过率（GFR）测量适用性。
General description
碘海醇是一种非离子型水溶性造影剂，用作测定肾功能水平的肾小球滤过率（GFR）的参考标记。它可以应用于血管造影和泌尿造影过程。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Development and validation of an HPLC-UV method for determination of iohexol in human plasma.
Soman R S, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 816(1-2), 339-343 (2005)
Human pharmacokinetics of iohexol. A new nonionic contrast medium.
BO, et al.
Investigative Radiology, 18(2), 177-182 (1983)
Iohexol clearance for GFR-determination in renal failure?single or multiple plasma sampling?.
Sterner G, et al.
Nephrology, Dialysis, and Transplantation, 11(3), 521-525 (1996)
Performance of iohexol determination in serum and urine by HPLC: validation, risk and uncertainty assessment.
Cavalier E, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 396(1-2), 80-85 (2008)
E Van de Kelft et al.
Neurosurgery, 28(4), 570-574 (1991-04-01)
Intracranial hemorrhage is an uncommon complication of dural puncture. In most instances, hematomas are subdural; they may be unilateral or bilateral. Rarely are intraparenchymal cerebral hemorrhages related to dural puncture. This report describes a delayed occurrence of bilateral intraparenchymal hemorrhages
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