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Merck
CN

73177

Supelco

2,4-二硝基氟苯

for HPLC derivatization, LiChropur, ≥99.0% (GC)

别名:

2,4-二硝基-1-氟苯, DNFB, DNPF, FDNB, 桑格试剂

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About This Item

线性分子式:
(O2N)2C6H3F
CAS号:
分子量:
186.10
Beilstein:
398632
EC 号:
MDL编号:
UNSPSC代码:
12000000
PubChem化学物质编号:
NACRES:
NA.22

等级

for HPLC derivatization

质量水平

方案

≥99.0% (GC)

表单

(Solid or Semi-Solid or Chunk(s) or Paste or Liquid)

质量

LiChropur

技术

HPLC: suitable

颜色

light yellow to very dark green-yellow, and Light Green to Very Dark Green

折射率

n20/D 1.569 (lit.)

沸点

178 °C/25 mmHg (lit.)

mp

25-27 °C (lit.)

密度

1.482 g/mL at 25 °C (lit.)

SMILES字符串

[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O

InChI

1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H

InChI key

LOTKRQAVGJMPNV-UHFFFAOYSA-N

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一般描述

1-氟-2,4-二硝基苯是一种颜色标记剂,主要用于检测伯胺和仲胺。

应用

1-氟-2,4-二硝基苯可作为衍生化试剂,用于高效液相色谱技术测定人血浆样品、药物制剂中的加巴喷丁和药物制剂中的盐酸美金刚。

推荐产品

探索最适于 HPLCLC-MS 分析的 LiChropur 试剂

法律信息

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

象形图

Health hazardExclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

327.2 °F

闪点(°C)

164 °C

法规信息

危险化学品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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访问文档库

A stability-indicating HPLC method for the determination of memantine hydrochloride in dosage forms through derivatization with 1-fluoro-2, 4-dinitrobenzene
Jalalizadeh H, et al.
Scientia Pharmaceutica, 82(2), 265-280 (2014)
Optimization of an HPLC method for determination of gabapentin in dosage forms through derivatization with 1-fluoro-2, 4-dinitrobenzene
Souri E, et al.
Chemical & Pharmaceutical Bulletin, 55(10), 1427-1430 (2007)
Validated HPLC method for the determination of gabapentin in human plasma using pre-column derivatization with 1-fluoro-2, 4-dinitrobenzene and its application to a pharmacokinetic study
Jalalizadeh H, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 854(1-2), 43-47 (2007)
Sonia Schuepbach-Mallepell et al.
The Journal of allergy and clinical immunology, 132(6), 1348-1357 (2013-08-21)
Innate immune sensors control key cytokines that regulate T-cell priming and T-cell fate. This is particularly evident in allergic reactions, which represent ideal systems to study the interplay of innate and adaptive immunity. In patients with contact dermatitis, inflammasome-mediated IL-1
Morten M Nielsen et al.
Journal of immunology (Baltimore, Md. : 1950), 192(7), 2975-2983 (2014-03-07)
Substances that penetrate the skin surface can act as allergens and induce a T cell-mediated inflammatory skin disease called contact hypersensitivity (CHS). IL-17 is a key cytokine in CHS and was originally thought to be produced solely by CD4(+) T

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