InChI key
ZJQHPWUVQPJPQT-UHFFFAOYSA-N
InChI
1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)
SMILES string
NCC1=CC(=O)NO1
Gene Information
rat ... Gabra2(29706)
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Biochem/physiol Actions
GABAA受体激动剂。
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - STOT SE 3
target_organs
Central nervous system
存储类别
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Pierre Le Merre et al.
Neuron, 97(1), 83-91 (2017-12-19)
The neural circuits underlying learning and execution of goal-directed behaviors remain to be determined. Here, through electrophysiological recordings, we investigated fast sensory processing across multiple cortical areas as mice learned to lick a reward spout in response to a brief
Babak K Mansoori et al.
Experimental neurology, 254, 18-28 (2014-01-23)
A rapidly growing number of studies using inhibition of the contralesional hemisphere after stroke are reporting improvement in motor performance of the paretic hand. These studies have used different treatment onset time, duration and non-invasive methods of inhibition. Whereas these
Daniela Popa et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(15), 6552-6556 (2013-04-12)
The cerebellum is an essential structure for the control of movement. It sends abundant ascending projections to the cerebral cortex via the thalamus, but its contribution to cortical activity remains largely unknown. Here we studied its influence on cortical neuronal
Thibault Cholvin et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(20), 8772-8783 (2013-05-17)
Electrophysiological and neuroanatomical evidence for reciprocal connections with the medial prefrontal cortex (mPFC) and the hippocampus make the reuniens and rhomboid (ReRh) thalamic nuclei a putatively major functional link for regulations of cortico-hippocampal interactions. In a first experiment using a
Jette G Petersen et al.
Journal of medicinal chemistry, 56(3), 993-1006 (2013-01-09)
A series of bioisosteric 4-(aminomethyl)-1-hydroxypyrazole (4-AHP) analogues of muscimol, a GABA(A) receptor agonist, has been synthesized and pharmacologically characterized at native and selected recombinant GABA(A) receptors. The unsubstituted 4-AHP analogue (2a) (EC(50) 19 μM, R(max) 69%) was a moderately potent
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