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等级
analytical standard
质量水平
方案
≥95.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤10.0% water (calc. from elemental analysis)
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
CN/C(NCCSCC1=CC=C(CN(C)C)O1)=C\[N+]([O-])=O.O
InChI
1S/C13H22N4O4S/c1-14-13(8-16(18)19)15-6-7-22-10-12-5-4-11(21-12)9-17(2,3)20/h4-5,8,14-15H,6-7,9-10H2,1-3H3/b13-8+
InChI key
DFJVUWAHTQPQCV-MDWZMJQESA-N
一般描述
Ranitidine N-oxide is a metabolite of the histamine antagonist drug ranitidine, which is prescribed for the treatment of duodenal and gastric ulcers.
应用
Ranitidine N-oxide may be used as an analytical reference standard for the determination of the analyte in biological fluids by high-performance liquid chromatography based technique.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Determination of ranitidine and its metabolites in human urine by reversed-phase ion-pair high-performance liquid chromatography
Carey PF, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 225(1), 161-168 (1981)
High-performance liquid chromatographic methods for the determination of ranitidine and its metabolites in biological fluids
Carey PF, et al.
Chromatographia, 19(1), 200-205 (1984)
Simple and universal HPLC-UV method to determine cimetidine, ranitidine, famotidine and nizatidine in urine: Application to the analysis of ranitidine and its metabolites in human volunteers
Ashiru, Diane AI , et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 860(2), 235-240 (2007)
M S Lant et al.
Journal of chromatography, 323(1), 143-152 (1985-04-17)
Reversed-phase high-performance liquid chromatography systems for the separation of ranitidine and its metabolites ranitidine-N-oxide, ranitidine-S-oxide, and desmethylranitidine have been developed for use in high-performance liquid chromatography-mass spectrometry. A direct liquid introduction-high-performance liquid chromatography-mass spectrometry system to analyse qualitatively and quantitatively
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