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Merck
CN

69532

Supelco

青蒿素

analytical standard

别名:

青蒿素

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About This Item

经验公式(希尔记法):
C15H22O5
CAS号:
分子量:
282.33
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

检测方案

≥98.0% (TLC)

旋光性

[α]/D +75.0±3°, c = 0.5 in methanol

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

156-157 °C (lit.)

应用

food and beverages

格式

neat

SMILES字符串

C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4

InChI

1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1

InChI key

BLUAFEHZUWYNDE-NNWCWBAJSA-N

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应用

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WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Moran Farhi et al.
Biotechnology & genetic engineering reviews, 29, 135-148 (2014-02-27)
Artemisinin, a natural compound from Artemisia annua, is highly effective in treating drug-resistant malaria. Because chemical synthesis of this natural terpenoid is not economically feasible, its only source remains as the native plant which produces only small quantities of it
Rick M Fairhurst et al.
The American journal of tropical medicine and hygiene, 87(2), 231-241 (2012-08-03)
Artemisinin-based combination therapies are the most effective drugs to treat Plasmodium falciparum malaria. Reduced sensitivity to artemisinin monotherapy, coupled with the emergence of parasite resistance to all partner drugs, threaten to place millions of patients at risk of inadequate treatment
Sanjeev Krishna et al.
Trends in parasitology, 29(7), 313-317 (2013-04-30)
The definition of artemisinin resistance is becoming one of a prolonged parasite clearance phenotype, although this variable is a complex function of both host and parasite characteristics. We discuss some of the limitations of this definition of artemisinin resistance, particularly
Debashish Das et al.
Malaria journal, 12, 125-125 (2013-04-23)
Parasitaemia on Day 3 has been proposed as a useful alert of potential artemisinin resistance, however, the normal variation of parasite clearance observed in artemisinin-based combination therapy clinical trials is poorly documented. The trends in early parasitological response following treatment
Nicholas M Njuguna et al.
Expert opinion on therapeutic patents, 22(10), 1179-1203 (2012-09-14)
The isolation of artemisinin from an ancient Chinese remedy in the early 1970s heralded the beginning of a new era in antimalarial drug therapy culminating in artemisinin-based combination therapies currently being the mainstay of malaria treatment worldwide. Ongoing research on

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