68527
哈巴俄苷
analytical standard
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关于此项目
经验公式（希尔记法）:
C24H30O11
化学文摘社编号:
分子量:
494.49
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
EC Number:
242-881-6
MDL number:
产品名称
哈巴俄苷, analytical standard
InChI key
KVRQGMOSZKPBNS-FMHLWDFHSA-N
InChI
1S/C24H30O11/c1-23(35-16(27)8-7-13-5-3-2-4-6-13)11-15(26)24(31)9-10-32-22(20(23)24)34-21-19(30)18(29)17(28)14(12-25)33-21/h2-10,14-15,17-22,25-26,28-31H,11-12H2,1H3/b8-7+/t14-,15-,17-,18+,19-,20-,21+,22+,23+,24-/m1/s1
SMILES string
C[C@@]1(C[C@@H](O)[C@]2(O)C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12)OC(=O)\C=C\c4ccccc4
grade
analytical standard
assay
≥95.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
Quality Level
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Harpagoside, a naturally occurring iridoid glycoside, is the main bioactive component of medicinal plants like Radix Scrophulariae, Scrophularia ningpoensis, Scrophularia buergeriana and Harpagophytum procumbens. It can exhibit a wide range of biological and pharmacological properties and hence used in the treatment of ailments like pharyngalgia, arthritis, rheumatism, tussis and constipation.
Simultaneous determination of harpagoside and cinnamic acid in rat plasma by high-performance liquid chromatography: application to a pharmacokinetic study
Li P, et al.
Analytical and Bioanalytical Chemistry, 389, 2259-2264 (2007)
Harpagoside: from Kalahari Desert to pharmacy shelf
Georgiev.IM, et al.
Phytochemistry, 92, 8-15 (2013)
Shengqiang Tong et al.
Phytochemical analysis : PCA, 17(6), 406-408 (2006-12-06)
The bioactive component harpagoside was successfully separated from the crude extract of Scrophularia ningpoensis Hemsley by one-step purification using high-speed counter-current chromatography (HSCCC). A two-phase solvent system containing n-butanol:ethyl acetate:water (1:9:10) was selected following consideration of the partition coefficient of
Eun Ju Jeong et al.
European journal of pharmacology, 588(1), 78-84 (2008-05-09)
The cognitive-enhancing activities of E-harpagoside and 8-O-E-p-methoxycinnamoylharpagide (MCA-Hg) isolated from Scrophularia buergeriana were evaluated in scopolamine-induced amnesic mice by the Morris water maze and by passive avoidance tests. E-harpagoside and MCA-Hg significantly improved the impairment of reference memory induced by
Cyril Colas et al.
Journal of chromatographic science, 46(2), 174-183 (2008-03-28)
Solid-phase extraction cartridges among those usually used for screening in horse doping analyses are tested to optimize the extraction of harpagoside (HS), harpagide (HG), and 8-para-coumaroyl harpagide (8PCHG) from plasma and urine. Extracts are analyzed by liquid chromatography coupled with
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