所有图片(2)
About This Item
经验公式（希尔记法）:
C19H30O5
CAS号:
分子量:
338.44
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
等级
analytical standard
质量水平
检测方案
≥97.0% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
格式
neat
SMILES字符串
O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O
InChI
1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
InChI key
JGPMMRGNQUBGND-UHFFFAOYSA-N
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应用
有关合适的仪器技术的更多信息，请参阅产品的分析证书。想要获得更多支持，请联系技术服务部。
生化/生理作用
一种短链辅酶 Q 类似物，可通过介导电子从 N2 转移到氧来增强超氧化物的形成。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Idebenone - monograph.
Alternative medicine review : a journal of clinical therapeutic, 6(1), 83-86 (2001-02-24)
Michael H Parkinson et al.
Journal of neurochemistry, 126 Suppl 1, 125-141 (2013-07-24)
Friedreich's ataxia is a debilitating progressive neurodegenerative disease associated with cardiomyopathy and other features. The underlying cause is a deficiency of the mitochondrial protein frataxin which causes mitochondrial iron deposition, increased oxidative stress and impaired adenosine triphosphate production. Over the
[The use of idebenone (noben) in neurological practice].
I V Damulin
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 106(11), 66-71 (2006-12-21)
Jörg B Schulz et al.
Journal of neurology, 256 Suppl 1, 42-45 (2009-04-11)
Several reports in the literature describe the effects of low-dose (5 mg/kg/day) idebenone in significantly reducing cardiac hypertrophy in patients with Friedreich ataxia. However, the effects of idebenone on neurological function have not been reliably determined in these studies; when
Claudia Becker et al.
Expert opinion on drug metabolism & toxicology, 6(11), 1437-1444 (2010-10-20)
Idebenone is a synthetic short chain benzoquinone that acts as an electron carrier in the mitochondrial electron transport chain, thereby, facilitating the production of ATP. In addition, idebenone is an antioxidant and can inhibit lipid peroxidation and may protect cell
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