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Merck
CN

65325

Sigma-Aldrich

8-Methoxypyrene-1,3,6-trisulfonic acid trisodium salt

for fluorescence, ≥98.0% (TLC)

别名:

PTS1, Trisodium 8-methoxypyrene-1,3,6-trisulfonate

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About This Item

经验公式(希尔记法):
C17H9Na3O10S3
CAS号:
分子量:
538.41
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.32

等级

for fluorescence

质量水平

检测方案

≥98.0% (TLC)

形式

solid

mp

253-260 °C (dec.) (lit.)

溶解性

DMF: soluble
DMSO: soluble
H2O: soluble
methanol: soluble

荧光

λex 404 nm; λem 431 nm in H2O

SMILES字符串

[Na+].[Na+].[Na+].COc1cc(c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C17H12O10S3.3Na/c1-27-12-6-13(28(18,19)20)9-4-5-11-15(30(24,25)26)7-14(29(21,22)23)10-3-2-8(12)16(9)17(10)11;;;/h2-7H,1H3,(H,18,19,20)(H,21,22,23)(H,24,25,26);;;/q;3*+1/p-3

InChI key

GUGNSJAORJLKGP-UHFFFAOYSA-K

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应用

8-Methoxypyrene-1,3,6-trisulfonic acid may be used as a fluorescent marker for studies of aerosolized drug delivery vehicles and as a highly water soluble superpolar fluorescent probe for assaying cationic surfactants

其他说明

Highly water soluble superpolar fluorescent probe for assaying cationic surfactants

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Moritz Beck-Broichsitter et al.
International journal of pharmaceutics, 367(1-2), 169-178 (2008-10-14)
The use of colloidal carrier systems for pulmonary drug delivery is an emerging field of interest in nanomedicine. The objective of this study was to compare the pulmonary absorption and distribution characteristics of the hydrophilic model drug 5(6)-carboxyfluorescein (CF) after
Kerstin Lahnstein et al.
International journal of pharmaceutics, 351(1-2), 158-164 (2007-11-06)
For the development of aerosolized controlled release formulations such as liposomes or nanoparticles, the use of suitable model drugs is necessary. This study compared the pulmonary absorption of the three structurally diverse fluorescent markers 5(6)-carboxyfluorescein (CF), 8-methoxypyrene-1,3,6-trisulfonic acid trisodium salt
Rania Salama et al.
Current drug delivery, 6(4), 404-414 (2009-06-19)
Delivering therapeutic agents to the airways maximizes their concentration in lung tissue, decreasing systemic exposure or facilitating systemic absorption as desired. Many formulations exist for the treatment of respiratory illnesses however, no controlled release inhalation formulation exists to-date. This review
S. Marhold et al.
Fresenius Journal of Analytical Chemistry, 336, 111-111 (1990)

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