所有图片(1)
别名:
甲基丙二酰氯
线性分子式:
CH3OCOCH2COCl
CAS号:
分子量:
136.53
Beilstein:
1754078
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
推荐产品
等级
purum
质量水平
检测方案
≥97.0% (AT)
折射率
n20/D 1.432 (lit.)
n20/D 1.432
bp
57-59 °C/12 mmHg (lit.)
密度
1.273 g/mL at 25 °C (lit.)
储存温度
2-8°C
SMILES字符串
COC(=O)CC(Cl)=O
InChI
1S/C4H5ClO3/c1-8-4(7)2-3(5)6/h2H2,1H3
InChI key
UTBCRHAMJFMIIR-UHFFFAOYSA-N
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应用
Methyl malonyl chloride can be used in the synthesis of methyl 7-hydroxy[1,3]thiazolo[5,4-b]pyridin-5(4H)-one-6-carboxylates and 6-carboxamides, which can act like HIV integrase strand transfer inhibitors. It can also be used in the synthesis of Strychnos alkaloids like (-)-leuconicine A and (-)-leuconicine B.
注意
储存中可能变黄
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
"Total synthesis of (-)-leuconicine A and B"
Sirasani G and Andrade.BR
Organic Letters, 13(17), 4736-4737 (2011)
"Synthesis and HIV-integrase strand transfer inhibition activity of 7-hydroxy [1, 3] thiazolo [5, 4-b]pyridin-5 (4H)-ones"
Boros.EE, et al.
Bioorganic & Medicinal Chemistry, 16(21), 5668-5672 (2006)
Elif Okutan et al.
Journal of fluorescence, 26(6), 2333-2343 (2016-11-01)
Colorimetric fluorescent chemosensors 4 and 5 based on mono- and di- styryl borondipyrromethenes (BODIPY) linked methyl malonyl were designed for detection of hemoglobin (HgB). Their sensing behavior toward various analytes (Br
实验方案
酸矿化后使用 Cuprizon 进行光度测定
Photometric determination with Cuprizon subsequent to acid mineralisation
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