等级
analytical standard
质量水平
检测方案
≥99% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
储存温度
2-8°C
InChI
1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)
InChI key
BMPDWHIDQYTSHX-UHFFFAOYSA-N
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一般描述
10,11-二氢-10-羟基卡马西平是一种10-羟基衍生物，是奥卡西平的活性代谢产物。
10,11-二氢-10-羟基卡马西平是抗癫痫药物奥卡西平的活性代谢物。
应用
10,11-二氢-10-羟基卡马西平可作为参比标准品，使用液相色谱法、 液相色谱串联质谱法 (LC-MS/MS) 和高效液相色谱串联紫外检测器 (HPLC-UV)测定生物样品中的 10,11-二氢-10-羟基卡马西平。
关于适当的仪器技术的更多信息，请参见产品的检验报告。联系技术服务部寻求进一步支持。
Shengyang Zhou et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1141, 122036-122036 (2020-02-29)
In this study, haptens were designed to produce highly sensitive and specific monoclonal antibodies (mAb) against carbamazepine (CBZ) and its metabolite carbamazepine-10, 11-epoxide (CBZ-EP). According to the results of our competitive enzyme-linked immunosorbent assay (ic-ELISA), the half-maximum inhibitory concentration values
First dose and steady-state pharmacokinetics of oxcarbazepine and its 10-hydroxy metabolite.
Dickinson R G, et al.
European Journal of Clinical Pharmacology, 37(1), 69-74 (1989)
Depression and Bipolar Disorder: Stahl's Essential Psychopharmacology, 3rd Edition (2008)
Simultaneous high-performance liquid chromatography determination of carbamazepine and five of its metabolites in plasma of epileptic patients.
Mandrioli R, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 762(2), 109-116 (2001)
Juhyun Sim et al.
Forensic science international, 274, 91-98 (2017-01-24)
In recent years, the inappropriate use of antipsychotics by young Korean men has become a social problem. As military service exemptions are given for mental illness, some men pose as mental health patients to avoid military service. In order to
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