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产品名称
N-羟基丁二酰亚胺, purum, ≥97.0% (T)
等级
purum
质量水平
方案
≥97.0% (T)
表单
solid
反应适用性
reaction type: Addition Reactions
mp
95-98 °C (lit.)
95-98 °C
应用
peptide synthesis
官能团
imide
SMILES字符串
ON1C(=O)CCC1=O
InChI
1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2
InChI key
NQTADLQHYWFPDB-UHFFFAOYSA-N
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应用
N-羟基丁二酰亚胺(NHS)可以用于以下实验:
- 合成N-琥珀星氩氨-3(2-吡啶二硫代)-酸酯,这是一种异双功能试剂,用于蛋白和蛋白偶联以及脂肪族硫醇插入蛋白。
- 合成长链脂肪酸的NHS酯
- NHS可以活化固定在钛表面的膦酸单层,用于结合蛋白。
其他说明
可能含有1-3%的丁二酸和或丁二酸酐
警示用语:
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Synthesis of long-chain fatty acyl-CoA thioesters using N-hydroxysuccinimide esters.
Methods in Enzymology, 72, 404-408 (1981)
Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio) propionate, a new heterobifunctional reagent.
The Biochemical Journal, 173(3), 723-723 (1978)
The Journal of chemical physics, 137(22), 224903-224903 (2012-12-20)
We investigated the relationship between the elastic modulus, G and the reaction probability, p for polymer networks. First, we pointed out that the elastic modulus is expressed by G = {(fp∕2 - 1) + O((p - 1)(2))} Nk(B)T∕V (percolated network
Phosphonic acid monolayers for binding of bioactive molecules to titanium surfaces.
Langmuir, 22(19), 8197-8204 (2006)
EMBO molecular medicine, 6(7), 918-936 (2014-06-13)
Despite the recent progress in the broad-scaled analysis of proteins in body fluids, there is still a lack in protein profiling approaches for biomarkers of rare diseases. Scarcity of samples is the main obstacle hindering attempts to apply discovery driven
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