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Merck
CN

55591

Supelco

羟甲唑啉 盐酸盐

analytical standard

别名:

2-(3-羟基-2,6-二甲基-4-叔丁基苄基)-2-咪唑啉 盐酸盐

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About This Item

经验公式(希尔记法):
C16H24N2O · HCl
CAS号:
分子量:
296.84
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:

等级

analytical standard

质量水平

检测方案

≥99.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

杂质

≤0.5% water

应用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

SMILES字符串

Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C

InChI

1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H

InChI key

BEEDODBODQVSIM-UHFFFAOYSA-N

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应用

Oxymetazoline hydrochloride may be used as a reference standard in the determination of oxymetazoline hydrochloride in nasal spray formulations using high performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化/生理作用

盐酸羟甲唑啉是一种部分 α2A-肾上腺素受体激动剂;5-HT1A、5-HT1B 和 5-HT1D 血清素受体的激动剂。它是 5-HT1C 血清素受体的混合激动剂-拮抗剂。

推荐产品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

象形图

Skull and crossbonesCorrosion

警示用语:

Danger

危险分类

Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1

WGK

WGK 3

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number

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Simultaneous determination of triamcinolone acetonide and oxymetazoline hydrochloride in nasal spray formulations by HPLC.
Sudsakorn S, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(5), 1273-1280 (2006)
Sylwia K Paszun et al.
Acta poloniae pharmaceutica, 70(6), 1079-1085 (2014-01-05)
The presented study aimed at the evaluation of hydrochlorothiazide influence on cilazapril stability in model mixture and fixed dose tablet formulation. The degradation of cilazapril in the presence of hydrochlorothiazide took place according to autocatalytic reaction kinetic mechanism, described mathematically

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