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Merck
CN

55206

Supelco

4-羟基苯乙酸

analytical standard

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别名:
p-Hydroxyphenyl acetic acid
线性分子式:
HOC6H4CH2CO2H
CAS号:
分子量:
152.15
Beilstein:
1448766
MDL编号:
UNSPSC代码:
41116107

等级

analytical standard

检测方案

≥97.5% (GC)

保质期

limited shelf life, expiry date on the label

mp

148-151 °C (lit.)

应用

clinical testing

格式

neat

SMILES字符串

OC(=O)Cc1ccc(O)cc1

InChI

1S/C8H8O3/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4,9H,5H2,(H,10,11)

InChI key

XQXPVVBIMDBYFF-UHFFFAOYSA-N

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一般描述

4-Hydroxyphenylacetic acid, a hydroxyphenylacetic acid metabolite, is reported to be produced via the bioactivation of kaempferol by intestinal microflora. It belongs to the class of dietary plant phenolic compounds, with a broad-spectrum of biological properties such as modulation of enzymatic activity, metal chelation, free radical scavenging, prevention of several human diseases, mainly atherosclerosis and cancer.

应用

4-Hydroxyphenylacetic acid may be used as an analytical reference standard for the quantification of the analyte in beer samples using high-performance liquid chromatography (HPLC) coupled to an electrochemical coulometric detector (ECD). It may also be used as an analytical standard for the quantification of the analyte in goat rumen fluid using HPLC with UV detection.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Quantitative determination of aromatic amino acids and related compounds in rumen fluid by high-performance liquid chromatography
Khan IR, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 710(1-2), 17-25 (1998)
Determination of free and bound phenolic acids in beer
Nardini M and Ghiselli A
Food Chemistry, 84(1), 137-143 (2004)
Cica Vissiennon et al.
The Journal of nutritional biochemistry, 23(7), 733-740 (2011-08-16)
Several in vivo and in vitro studies have confirmed that flavonols are metabolized by the intestinal microflora to their corresponding hydroxyphenylacetic acids. In this article, a comparison of the anxiolytic activity of the flavonols kaempferol, quercetin and myricetin in the

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