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Merck
CN

50202

Supelco

四氢姜黄素

analytical standard

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别名:
1,7-双(4-羟基-3-甲氧基苯基)-3,5-庚二酮
经验公式(希尔记法):
C21H24O6
CAS号:
分子量:
372.41
Beilstein:
3485469
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

检测方案

≥95.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

food and beverages

格式

neat

SMILES字符串

COc1cc(CCC(=O)CC(=O)CCc2ccc(O)c(OC)c2)ccc1O

InChI

1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3

InChI key

LBTVHXHERHESKG-UHFFFAOYSA-N

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一般描述

四氢姜黄素是一种无色化合物,以及姜黄素的主要代谢产物。已知其具有抗氧化活性和对叔丁基过氧化氢诱导的脂质过氧化的抑制作用。 其可以通过在氧化铂(IV)存在下氢化姜黄素获得。

应用

有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务。

包装

无底玻璃瓶。内含物在插入的融合锥体内。

WGK

WGK 3

闪点(°F)

385.2 °F

闪点(°C)

196.2 °C


分析证书(COA)

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Leelavinothan Pari et al.
Molecular and cellular biochemistry, 341(1-2), 109-117 (2010-03-27)
The present study evaluates the combined effect of tetrahydrocurcumin and chlorogenic acid on oxidative stress in streptozotocin-nicotinamide-induced diabetic rats. Rats were rendered diabetic by a single intraperitoneal injection (i.p) of streptozotocin (45 mg/kg BW), 15 min after an i.p injection
Namfa Sermkaew et al.
AAPS PharmSciTech, 14(1), 321-331 (2013-01-16)
Novel self-microemulsifying floating tablets were developed to enhance the dissolution and oral absorption of the poorly water-soluble tetrahydrocurcumin (THC). Their physicochemical properties and THC permeability across Caco-2 cell monolayers were assessed. The self-microemulsifying liquid containing THC was adsorbed onto colloidal
Neetu Tyagi et al.
Journal of molecular neuroscience : MN, 47(1), 128-138 (2012-01-04)
High levels of homocysteine (Hcy) known as hyperhomocysteinemia (HHcy), contribute to autophagy and ischemia/reperfusion injury (I/R). Previous studies have shown that I/R injury and HHcy cause increased cerebrovascular permeability; however, the associated mechanism remains obscure. Interestingly, during HHcy, cytochome-c becomes
Saipin Setthacheewakul et al.
AAPS PharmSciTech, 12(1), 152-164 (2010-12-25)
The objectives of this study were to develop and evaluate a novel self-emulsifying floating drug delivery system (SEFDDS) that resulted in improved solubility, dissolution, and controlled release of the poorly water-soluble tetrahydrocurcumin (THC). The formulations of liquid self-emulsifying drug delivery
Involvement of the ?-diketone moiety in the antioxidative mechanism of tetrahydrocurcumin
Sugiyama Y, et al.
Biochemical Pharmacology, 52, 519-525 (1996)

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