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Merck
CN

49724

丹酚酸 B

analytical standard

别名:

(2 S ,3 S )-4-[(1 E )-3-[(1 R )-1-羧基-2-（3,4-二羟基苯基）乙氧基]-3-氧代-1-丙烯-1-基]-2-（3,4-二羟基苯基）-2,3-二氢-7-羟基-3-苯并呋喃羧酸 3-[(1 R )-1-羧基-2-（3,4-二羟基苯基）乙基] 酯, 丹参酸 B, 丹芬酸 B, 紫草酸 B

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关于此项目

经验公式（希尔记法）:
C36H30O16
化学文摘社编号:
121521-90-2
分子量:
718.61
NACRES:
NA.24
PubChem Substance ID:
329757512
UNSPSC Code:
85151701
MDL number:
MFCD23115783

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InChI key

SNKFFCBZYFGCQN-VWUOOIFGSA-N

SMILES string

OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c3O[C@@H]([C@@H](C(=O)O[C@H](Cc4ccc(O)c(O)c4)C(O)=O)c23)c5ccc(O)c(O)c5

InChI

1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31+,32-/m1/s1

grade

analytical standard

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

100

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相关类别

General description

Salvianolic acid B is a cell protective antioxidant and free radical scavenger being investigated for a variety of conditions from ischemic heart disorders to Alzheimer′s disease.
Salvianolic acid B is one of the main water soluble bioactive components of Salvia miltiorrhiza medicinal plant, the root of which is used in the treatment of dysmenorrhea, coronary heart disease, chronic renal failure, cerebrovascular disease, hypertension, and cytotoxicity against human tumor cell lines.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Salvianolic acid B may be used as an analytical reference standard for the quantification of the anayte in the roots of Salvia miltiorrhiza and other related Chinese medicines using chromatography techniques.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: salvia

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN5543
BCCM1718
BCCJ9596
BCCH9727
BCCG9796

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Isolation and purification of salvianolic acid A and salvianolic acid B from Salvia miltiorrhiza by high-speed counter-current chromatography and comparison of their antioxidant activity.
Sun Y, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(8-9), 733-737 (2009)
H Yamamoto et al.
Journal of chromatography. B, Biomedical sciences and applications, 738(1), 3-15 (2000-04-25)
A high-performance liquid chromatography (HPLC) analysis system based on a water-acetonitrile gradient program was established for simultaneous quantification of shikimate-derived secondary metabolites in cultured cells of Lithospermum erythrorhizon. The cells cultured in pigment production medium (M-9) are capable of producing
Anja Watzke et al.
Journal of natural products, 69(8), 1231-1233 (2006-08-29)
Salvianolic acid B and lithospermic acid B are the major components of Salvia miltiorrhiza, which is one of the most popular herbal traditional medicines in Asian countries. Salvianolic acid B and lithospermic acid B are reported to have identical structures
Xiaochuan Li et al.
Drug metabolism and disposition: the biological fate of chemicals, 35(2), 234-239 (2006-11-30)
Salviae miltiorrhiza, a traditional Chinese medical herb known as "Danshen," has been widely used in clinics to improve blood circulation, relieve blood stasis, and treat coronary heart disease. Depside salts from S. miltiorrhiza are a novel drug in which magnesium
Y X Guo et al.
Ultrasonics sonochemistry, 19(4), 719-724 (2012-01-24)
We studied the effect of ultrasonication extraction technology combined with ammonium sulfate/ethanol aqueous two-phase system (ATPS) for the separation of lithospermic acid B (LAB) from Salvia miltiorrhiza Bunge. According to the literature and preliminary studies, ammonium sulfate concentration, ethanol concentration
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