484407
1-甲氧基-2-丙醇
≥99.5%
别名:
DOWANOL® PM, 丙二醇单甲醚, 丙二醇甲醚
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线性分子式:
CH3CH(OH)CH2OCH3
化学文摘社编号:
分子量:
90.12
UNSPSC Code:
12352100
NACRES:
NA.21
PubChem Substance ID:
EC Number:
203-539-1
Beilstein/REAXYS Number:
1731270
MDL number:
Assay:
≥99.5%
Vapor pressure:
10.9 mmHg ( 25 °C)
InChI key
ARXJGSRGQADJSQ-UHFFFAOYSA-N
InChI
1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3
SMILES string
CC(O)COC
vapor density
3.12 (vs air)
vapor pressure
10.9 mmHg ( 25 °C)
product line
ReagentPlus®
assay
≥99.5%
Quality Level
autoignition temp.
532 °F
expl. lim.
13.8 %
greener alternative product characteristics
Safer Solvents and Auxiliaries
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sustainability
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impurities
≤0.001% water
mp
-97 °C
solubility
water: miscible
density
0.916 g/mL at 25 °C (lit.)
application(s)
microbiology
greener alternative category
, Aligned
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General description
1-甲氧基-2-丙醇(丙二醇甲醚，PGME)，是一种甘醇醚，可通过在ZnMgAl（锌-镁-铝）催化剂存在下由环氧丙烷与甲醇反应进行合成。它在不同土壤类型中的微生物降解已被研究。通过对F344大鼠和B6C3F1小鼠的吸入研究，已得到PGME的口服参考剂量（RfD）和吸入参考浓度（RfC）值。
我们致力于为您提供更环保的替代产品，以符合“绿色化学的 12 项原则”的一项或多项原则要求。单醚，特别是丙二醇甲醚（PGME）作为一种无污染溶剂已广泛应用于制药、化工和化装品行业的精细有机合成应用中，符合“更安全的溶剂和辅助剂”的要求。 点击此处了解更多信息。
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Flam. Liq. 3 - STOT SE 3
target_organs
Central nervous system
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
88.7 °F - closed cup - (External MSDS)
flash_point_c
31.5 °C - closed cup - (External MSDS)
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
Influence of acid-base properties of ZnMgAl-mixed oxides for the synthesis of 1-methoxy-2-propanol.
Cheng W, et al.
Applied Clay Science, 42(1), 111-115 (2008)
Biodegradation of glycol ethers in soil.
Gonsior SJ and West RJ.
Environmental Toxicology and Chemistry / Setac, 14(8), 1273-1279 (1995)
Rei Momose et al.
Organic letters, 15(8), 2010-2013 (2013-04-11)
Three new alkaloids, hyrtimomines A-C (1-3), were isolated from an Okinawan marine sponge Hyrtios sp. The structures of 1-3 were elucidated on the basis of spectroscopic analysis and application of a phenylglycine methyl ester (PGME) method. Hyrtimomines A (1) and
J Y Domoradzki et al.
Toxicological sciences : an official journal of the Society of Toxicology, 75(1), 31-39 (2003-07-15)
The kinetic equivalency of propylene glycol monomethyl ether (PGME), derived from propylene glycol monomethyl ether acetate (PGMEA), as well as the parent compound (PGME) following intravenous administration to Fischer 344 rats was evaluated. In addition, in vitro hydrolysis rates of
Nancy B Hopf et al.
Toxicology letters, 211(1), 77-84 (2012-03-17)
Aging adults represent the fastest growing population segment in many countries. Physiological and metabolic changes in the aging process may alter how aging adults biologically respond to pollutants. In a controlled human toxicokinetic study (exposure chamber; 12 m³), aging volunteers
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