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安全信息

484407

Sigma-Aldrich

1-甲氧基-2-丙醇

greener alternative

≥99.5%

别名:

DOWANOL® PM, 丙二醇单甲醚, 丙二醇甲醚

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About This Item

线性分子式:
CH3CH(OH)CH2OCH3
CAS号:
107-98-2
分子量:
90.12
Beilstein:
1731270
EC 号:
203-539-1
MDL编号:
MFCD00004537
UNSPSC代码:
12352100
PubChem化学物质编号:
57651153
NACRES:
NA.21
方案:
≥99.5%
应用:
microbiology
沸点:
118-119 °C (lit.)
蒸汽压:
10.9 mmHg ( 25 °C)

蒸汽密度

3.12 (vs air)

质量水平

200

蒸汽压

10.9 mmHg ( 25 °C)

产品线

ReagentPlus®

方案

≥99.5%

表单

liquid

自燃温度

532 °F

expl. lim.

13.8 %

环保替代产品特性

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

杂质

≤0.001% water

折射率

n20/D 1.403 (lit.)

沸点

118-119 °C (lit.)

mp

-97 °C

溶解性

water: miscible

密度

0.916 g/mL at 25 °C (lit.)

应用

microbiology

环保替代产品分类

, Aligned

SMILES字符串

CC(O)COC

InChI

1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3

InChI key

ARXJGSRGQADJSQ-UHFFFAOYSA-N

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相关类别

一般描述

1-甲氧基-2-丙醇(丙二醇甲醚，PGME)，是一种甘醇醚，可通过在ZnMgAl（锌-镁-铝）催化剂存在下由环氧丙烷与甲醇反应进行合成。它在不同土壤类型中的微生物降解已被研究。通过对F344大鼠和B6C3F1小鼠的吸入研究，已得到PGME的口服参考剂量（RfD）和吸入参考浓度（RfC）值。
我们致力于为您提供更环保的替代产品，以符合“绿色化学的 12 项原则”的一项或多项原则要求。单醚，特别是丙二醇甲醚（PGME）作为一种无污染溶剂已广泛应用于制药、化工和化装品行业的精细有机合成应用中，符合“更安全的溶剂和辅助剂”的要求。 点击此处了解更多信息。

法律信息

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

FlameExclamation mark
GHS02,GHS07

警示用语：

Warning

危险声明

H226,H336

危险分类

Flam. Liq. 3 - STOT SE 3

靶器官

Central nervous system

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

88.7 °F - closed cup - (External MSDS)

闪点(°C)

31.5 °C - closed cup - (External MSDS)

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
STBL4198
MKCW2242
MKCW0598
MKCW1794
SDBB1290

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Influence of acid-base properties of ZnMgAl-mixed oxides for the synthesis of 1-methoxy-2-propanol.
Cheng W, et al.
Applied Clay Science, 42(1), 111-115 (2008)
Biodegradation of glycol ethers in soil.
Gonsior SJ and West RJ.
Environmental Toxicology and Chemistry / Setac, 14(8), 1273-1279 (1995)
Rei Momose et al.
Organic letters, 15(8), 2010-2013 (2013-04-11)
Three new alkaloids, hyrtimomines A-C (1-3), were isolated from an Okinawan marine sponge Hyrtios sp. The structures of 1-3 were elucidated on the basis of spectroscopic analysis and application of a phenylglycine methyl ester (PGME) method. Hyrtimomines A (1) and
Nancy B Hopf et al.
Toxicology letters, 211(1), 77-84 (2012-03-17)
Aging adults represent the fastest growing population segment in many countries. Physiological and metabolic changes in the aging process may alter how aging adults biologically respond to pollutants. In a controlled human toxicokinetic study (exposure chamber; 12 m³), aging volunteers
J Y Domoradzki et al.
Toxicological sciences : an official journal of the Society of Toxicology, 75(1), 31-39 (2003-07-15)
The kinetic equivalency of propylene glycol monomethyl ether (PGME), derived from propylene glycol monomethyl ether acetate (PGMEA), as well as the parent compound (PGME) following intravenous administration to Fischer 344 rats was evaluated. In addition, in vitro hydrolysis rates of
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