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Merck
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安全信息

46609

Supelco

青霉素G 钾盐

VETRANAL®, analytical standard

别名:

苄青霉素 钾盐

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About This Item

经验公式（希尔记法）:
C16H17KN2O4S
CAS号:
113-98-4
分子量:
372.48
Beilstein:
3832841
EC 号:
204-038-0
MDL编号:
MFCD00036193
UNSPSC代码:
41116107
PubChem化学物质编号:
329757219
E编号:
E705
NACRES:
NA.24

等级

analytical standard

质量水平

100

Agency

EPA 1694

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

抗生素抗菌谱

Gram-positive bacteria

应用

cleaning products
clinical
cosmetics
environmental
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

格式

neat

作用机制

cell wall synthesis | interferes

储存温度

2-8°C

SMILES字符串

[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

IYNDLOXRXUOGIU-LQDWTQKMSA-M

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相关类别

一般描述

化学结构:β-内酰胺

应用

有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
青霉素G(Penicillin G)是源自肺炎链球菌(Streptococcus pneumoniae)的窄谱抗生素。 可用于治疗A、B、C和G族链球菌、非肠球菌类D族链球菌、草绿色链球菌和不产青霉素酶的链球菌。 钾盐形式已用于研究葡萄球菌的胞壁体(murosome)以及青霉素诱导的变形链球菌裂解。

生化/生理作用

作用机制：青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联，从而抑制细胞壁合成。

抗菌谱：本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。

注意

溶液应过滤除菌，2-8℃可储存1周，-20°C可保存更长时间。 溶液在 37°C 下可稳定保存 3 天。 钠盐形式可以100 mg/mL溶于水。

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H317

危险分类

Skin Sens. 1

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

监管及禁止进口产品

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分析证书(COA)

Lot/Batch Number
BCCJ2888
BCCJ0891
BCCG9607
BCCF9327
BCCD6729

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Vasim Ahmed et al.
Journal of biotechnology, 163(4), 419-424 (2013-01-12)
In the present study, a novel strategy was adopted to synthesize, β lactamase resistant penicillin G molecules by using the unique properties of silver nanoparticles. Ascorbic acid-stabilized spherical monodispersed silver nanoparticles were prepared by a simple chemical reaction. The formation
Tina Lund Leunbach et al.
Ugeskrift for laeger, 175(11), 742-743 (2013-03-14)
A pregnant Caucasian woman with newly diagnosed syphilis in the secondary stage was hospitalized for observation while being treated with penicillin. After one dose of penicillin the foetus was delivered by a caesarean section at gestational age 28 weeks +
Muneki Hotomi et al.
PloS one, 8(3), e58124-e58124 (2013-03-14)
The protection against pneumococcal infections provided by currently available pneumococcal polysaccharide conjugate vaccines are restricted to the limited number of the serotypes included in the vaccine. In the present study, we evaluated the distribution of the pneumococcal capsular type and
Eleonor G Lago et al.
Sexually transmitted diseases, 40(2), 85-94 (2013-01-18)
The aim of this study was to investigate clinical features and outcomes of children treated for congenital syphilis (CS). Infants born alive in the public sector of São Lucas Hospital, Porto Alegre, Brazil, 1997 to 2004, whose mothers had syphilis
Lemierre's syndrome in systemic lupus erythematosus: a report of two cases.
J C Rødgaard et al.
Scandinavian journal of rheumatology, 42(2), 167-168 (2013-01-15)
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