46494
硝呋齐特
VETRANAL®, analytical standard
别名:
4-羟基-2′-(5-硝基呋喃甲叉)-苯酰肼
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关于此项目
经验公式（希尔记法）:
C12H9N3O5
化学文摘社编号:
分子量:
275.22
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
213-522-0
Beilstein/REAXYS Number:
4264976
MDL number:
InChI key
YCWSUKQGVSGXJO-NTUHNPAUSA-N
InChI
1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+
SMILES string
Oc1ccc(cc1)C(=O)N\N=C\c2ccc(o2)[N+]([O-])=O
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
Quality Level
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General description
Nifuroxazide is an oral antibiotic, which may be used for the treatment of diarrhea.
Application
Nifuroxazide may be used as a reference standard in the determination of the analyte in plasma samples using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
Mariane B Fernandes et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(3), 535-540 (2012-01-31)
It is important to determine the toxicity of compounds and co-solvents that are used in cell monolayer permeability studies to increase confidence in the results obtained from these in vitro experiments. This study was designed to evaluate the cytotoxicity of
JAK-STAT Pathway in Disease (2009)
Fávero Reisdorfer Paula et al.
Bioorganic & medicinal chemistry, 17(7), 2673-2679 (2009-03-24)
In this study, in vitro anti-T. cruzi activity assays of nifuroxazide (NX) analogues, such as 5-nitro-2-furfuryliden and 5-nitro-2-theniliden derivatives, were performed. A molecular modeling approach was also carried out to relate the lipophilicity potential (LP) property and biological activity data.
Akilimali Shindano et al.
Acta gastro-enterologica Belgica, 70(1), 32-33 (2007-07-11)
We report the case of a middle-aged woman who developed a typical picture of acute pancreatitis together with systemic features of immunoallergy after the intake of two capsules (200 mg) of nifuroxazide. Even if acute pancreatitis is a rare adverse
Philippe Quillardet et al.
Mutagenesis, 21(5), 305-311 (2006-08-10)
Nitrofurans are widely used in human medicine, as nitrofurantoin and nifuroxazide, still prescribed for long-term antimicrobial prophylaxis of urinary tract and gastrointestinal infection in humans respectively. Recent experiments in mammals, as well as reports mentioning toxic effects in humans associated
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