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Merck
CN

46036

Supelco

溴鼠隆

PESTANAL®, analytical standard

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经验公式(希尔记法):
C31H23BrO3
CAS号:
分子量:
523.42
Beilstein:
8171403
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

产品线

PESTANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

agriculture
environmental

格式

neat

SMILES字符串

OC1=C(C2CC(Cc3ccccc23)c4ccc(cc4)-c5ccc(Br)cc5)C(=O)Oc6ccccc16

InChI

1S/C31H23BrO3/c32-24-15-13-20(14-16-24)19-9-11-21(12-10-19)23-17-22-5-1-2-6-25(22)27(18-23)29-30(33)26-7-3-4-8-28(26)35-31(29)34/h1-16,23,27,33H,17-18H2

InChI key

VEUZZDOCACZPRY-UHFFFAOYSA-N

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一般描述

Brodifacoum is an anticoagulant rodenticide, widely used for the control of rodent population via inhibition of the vitamin K epoxide reductase, causing blood clotting alterations, leading to haemorrhaging as the ultimate cause of death.

应用

Brodifacoum may be used as an analytical reference standard for the quantification of the analyte in animal samples and biological samples using different chromatography techniques..
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1A - STOT RE 1

靶器官

Blood

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. For what applications can Product 46036, Brodifacoum, be used?

    This product consists of a coumarin analog. It has anticoagulant activity and has been described as a rodenticide.

  6. What is the purity of Product 46036, Brodifacoum?

    This product does not have a purity specification. However, the purity is provided on the certificate of analysis of each lot.

  7. What is Product 46036, Brodifacoum, soluble in?

    This product is insoluble in water. It is slightly soluble in alcohol and benzene. It is soluble in acetone and chloroform.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

The determination of the anticoagulant rodenticide brodifacoum in blood serum by liquid chromatography with fluorescence detection
Felice.JL and Murphy.JM
Journal of Analytical Toxicology, 13(4), 229-231 (1989)
Naren Gunja et al.
Clinical toxicology (Philadelphia, Pa.), 49(5), 385-390 (2011-07-12)
Brodifacoum is a widely available superwarfarin used as a commercial rodenticide. Toxicity from long-acting anticoagulant rodenticides, primarily from uncontrolled bleeding, has been reported. Very little published toxicokinetic data are available for human brodifacoum poisoning. Management is also contentious with uncertainty
Servet Altay et al.
Cardiovascular journal of Africa, 23(9), e9-e11 (2012-10-31)
Superwarfarins (brodifacoum, difenacoum, bromodialone and chlorphacinone) are anticoagulant rodenticides that were developed in 1970s to overcome resistance to warfarin in rats. A 26-year-old previously healthy man was admitted to the emergency department with epigastric pain, severe upper and lower gastrointestinal
Alan P Buckle et al.
Pest management science, 68(12), 1579-1585 (2012-09-26)
The tyrosine to cysteine amino acid substitution at location 139 of the vkorc1 protein (i.e. tyrosine139cysteine or Y139C) is the most widespread anticoagulant resistance mutation in Norway rats (Rattus norvegicus Berk.) in Europe. Field trials were conducted to determine the
Manifestations of superwarfarin ingestion: a plea to increase awareness.
Dipika Misra et al.
American journal of hematology, 85(5), 391-392 (2010-03-17)

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